Pure Riluzole Powder CAS 1744-22-5

Riluzole Introduction

Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.

As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.

Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.

The appearance of Pure Riluzole Powder is white powder. Its CAS number is 1744-22-5 and its molecular formula is C8H5F3N2OS. Molecular weight: 234.2; EINECS number: 605-724-6belongs to the benzothiazole class of compounds and is currently the only product approved by the US Food and Drug Administration (FDA) for the treatment of amyotrophic lateral sclerosis. It mainly works by regulating the concentration of glutamate and acting on ion channels. Clinically used for the treatment of amyotrophic lateral sclerosis, prolonging life or mechanical ventilation time, but not applicable to other forms of motor neuron diseases. High quality Riluzoler is a white solid powder that can crystallize in ethanol solutions of specific purity, with a melting point of 119 ℃.

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What is the relationship between Amyotrophic Lateral Sclerosis and Riluzole?

Due to the degeneration of motor neurons, patients can't normally control the nerve impulses transmitted by muscle fibers in muscle movement as usual, which leads to the phenomenon of muscle weakness. This is amyotrophic lateral sclerosis, which is a fatal progressive neurodegeneration caused by motor nerve degeneration, characterized by the gradual degeneration of nerve cells in the central nervous system that control the movement of striated muscles. 98% Pure Riluzole Powder is a glutamate antagonist. 1. This product can inhibit the release of neurotransmitters in the brain, inhibit the synaptic transmission of glutamate, and inhibit the reuptake of γ -aminobutyric acid (GABA), dopamine and glutamic acid; 2. This product can also significantly inhibit the activity of excitatory amino acids; 3. This product can also stabilize the inactivation state of voltage-dependent sodium channels, and these obvious neuroprotective effects are helpful to delay the apoptosis of motor neurons. However, because there is no definite research result on the causes of neuronal apoptosis so far, this product has no function of reversing necrotic neurons.

Further research on Riluzole

An animal experiment showed that riluzole could prolong the survival time of ALS transgenic animal models. Many animal models of nerve excitability injury have shown that riluzole has a neuroprotective effect. In vitro studies showed that riluzole could protect cultured rat motor neurons from excitotoxic injury of glutamate and inhibit cortical cell death caused by hypoxia.
There is no evidence that Riluzole has a therapeutic effect on motor function, lung function, muscle bundle tremor, muscle strength, and motor symptoms. Riluzole did not show efficacy in patients with advanced ALS. Currently, the safety and effectiveness of riluzole has only been studied in ALS.Therefore, Pure Riluzole Powder should not be used for any other type of motor neuron disease.

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FAQ:

Q1:What advantages does Riluzole have for lab research?
It works on both glutamate secretion and sodium channel stabilization, a classic reference compound for glutamate pathway tests.
Q2:What is the main target of Riluzole?
It suppresses excessive glutamate release and blocks overactive excitatory neural signals for nerve-related mechanism research.
Q3:How to store Riluzole properly?

Seal tightly, store at 2–8°C away from light and heat to avoid degradation and impurity growth.

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Pure Riluzole Powder etc. at a more favorable price. If you are interested, please leave a message.

We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

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