Memantine hydrochloride powder, developed by Merz company, Germany, is a novel antagonist of n-methyl-d-aspartate (NMDA) receptor with low to moderate affinity, voltage dependence, and non-competition, which can block NMDA receptor uncompetitive, reduce NMDA receptor overexcitation caused by glutamic acid, prevent apoptosis and improve memory, and is a new generation to improve cognitive function.
Huperzine A is a drug extracted from Huperzia Serrata, a traditional Chinese medicine, and is a reversible competitive cholinesterase inhibitor. It has different binding abilities to different glutamate receptor subtypes or their ion channels, thus reducing the excitotoxicity of glutamate and treating AD. Patients with AD not only have changes in a variety of neurotransmitters but also have abnormal postsynaptic receptors, so the use of cholinesterase inhibitors and glutamate receptor inhibitors can play a synergistic role.
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| Real shot pictures of Memantine HCL powder | Memantine HCL powder structure diagram |
Product Application
1. Memantine hydrochloride powder can promote the release of central dopamine, directly or indirectly excite dopamine receptors, and play an anti-paralysis role.
2. It is used to prevent the progression of dementia symptoms in patients with moderate and severe Alzheimer's dementia.
Product Specification
Item | Specification | Results |
Appearance | The white or almost white crystalline powder | White crystalline powder |
Identification | IR: Must conform to reference standard | Conforms |
PH | 4.5~5.5 | 5.3 |
Loss on drying | Not more than 0.5% | 0.27% |
Residue on ignition | Not more than 0.1% | 0.07% |
Heavy metals | Not more than 10ppm | <10ppm |
Related substances (HPLC) 1-methyladamantane 1,3,5-Trimethyladamantane Unknown impurity Total impurities | Not more than 0.3% Not more than 0.3% Not more than 0.1% Not more than 0.5% | 0.13% 0.14% <0.1% <0.4% |
Residual solvent Ethanol Ethyl acetate | Not more than 0.5% Not more than 0.5% | 0.12% 0.07% |
Assay (HPLC) | 98.5%~101.0%(On a dried basis) | 99.6% |
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A variety of shipping methods for you to choose
Transportation Time | Shipping method | Cargo weight requirements | Advantage |
3-7 days | DHL,Germany DHL,Germany DPD, | Suitable for under 50kg. | We have warehouses in Germany and California, the USA, |
7-15 days | By Air | Suitable for more than 50kg. | |
15-60 days | By Sea | Suitable for more than 500kg. |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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