Ceramides Skin Powder CAS 100403-19-8

Ceramides skin Powder are a kind of sphingosine lipid composed of sphingosine long-chain bases and fatty acids. They exist in all eukaryotic cells and play an important role in regulating cell differentiation, proliferation, apoptosis, aging, and other life activities. Ceramide 3% (rice bran), as the main component of intercellular lipids in the skin stratum corneum, not only acts as a second messenger molecule in the sphingomyelin pathway but also plays an important role in the formation of the epidermal stratum corneum. It has the functions of maintaining skin barrier, moisturizing, anti-aging, whitening, and disease treatment.

What is the relationship between skin and ceramide?

Ceramides skin Powder is the main component (> 50%) of intercellular lipids in the outermost stratum corneum of human skin. It plays an important role in preventing moisture emission and external stimulation. It undertakes the functions of protecting skin, moisturizing and moisturizing. There are also many research reports that the use of topical ointment products containing ceramide can achieve the purpose of preventing allergic skin diseases and the effect of inhibiting melanin brown spots.

With the increase of age and entering old age, the ceramide in human skin will gradually decrease. The occurrence of abnormal skin symptoms such as dry skin and rough skin is also due to the decrease of ceramide. In most cases, ceramide used in cosmetics is synthetic (whether ceramide or ceramide-like). Because the content of ceramide in plants is too low and it is too expensive to extract from animals, this product cannot be popularized. Until the development of biotechnology in recent years, the latest generation of moisturizers developed contained ceramide with different contents, It is a water-soluble lipid material, and because the structure of this product is similar to that of the material constituting the cuticle of the skin, it can quickly penetrate into the skin to form a network of water lipid molecular structure and lock in water. Experiments have proved that both synthetic and natural extraction can achieve the same effect as long as the chemical structure is the same.

What is ceramide extracted from? How many kinds of ceramide are there?

In the early stage, abundant Ceramides skin Powder was mainly extracted from animal brains, such as the bovine brain. However, since the occurrence of mad cow disease in 1986, Ceramide 3 products extracted from animal brain tissue have been replaced by plant ceramide, which has high safety and easy absorption, and has become the main force of market production At present, the market is mainly made of rice, wheat, corn, konjac, and other raw materials. The plant ceramide sold by our company has the characteristics of high content, low price, and wide product types. It is suitable for various purposes and is favored by many sellers.

With technological innovation, our company has developed two new synthetic methods: chemical synthesis and microbial fermentation. The main chemical synthesis is pseudo ceramide. Its structure is similar to ceramide and its function is similar. It can be used in cosmetics. A variety of pseudo ceramide has been preliminarily synthesized. Microbial fermentation mainly uses Pichia pastors or Saccharomyces cerevisiae to ferment to obtain tetra acetyl plant sphingosine in a certain environment, then deacetylate it to obtain plant sphingosine, and add fatty acids to synthesize ceramide and other substances. This method has a long cycle and high price, but it can meet much scientific research and meet the goal of carbon neutralization development in the future.

What is the market prospect of ceramide? Can ceramide be used for a long time?

In Japan, Ceramides skin Powder was listed in the 1990s. Nowadays, it is selling like hotcakes. Besides the addition of vegetable ceramide to common cosmetics, it is also a hot spot in functional food and medicine. I believe this product will remain one of the main products of our company in the foreseeable future.

Medically, ceramide plays an important messenger role in the biological effects induced by various cytokines, vitamin D3, Fas, and CD28 ligands, and its role in mediating apoptosis has attracted increasing attention. At the same time, ceramide is also involved in many physiological and pathological processes such as cell differentiation. In the process of epidermal keratinocyte culture, ceramide can induce apoptosis. Ceramide is the decomposition product of sphingomyelin in the bilayer of biofilm, and it is recognized as the second messenger. In addition, ceramide plays an extensive and important role in the process of cell growth, proliferation, differentiation, apoptosis, and injury.

In the food industry, many health foods have been developed by using some physiological functions of ceramide, which can inhibit the rise of blood pressure, activate immunity, hinder lipase activity and inhibit the proliferation of cancer cells. Plant ceramide products were also commercialized and put on the market in 1998. So far, its commodities are mainly functional drinks, tablets and other nutritional supplements, and health foods.

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