In the research and development of whitening cosmetics, what are the tricks to reduce melanin?
Raw powder 4-Butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but its whitening activity also has a synergistic effect in the process.
It is a chemical substance commonly used as a whitening additive for skin care products. Its chemical formula is C10H14O2 and its molecular weight is 166.22. It is actually a whitening ingredient.
We see these in many beauty products and skincare products: Tetrahydrocurcumin, nicotinamide, arbutin, Tranexamic acid, phloretin, glycyrrhizin, resveratrol, ferulic acid, vitamin C and its Derivatives (VC ethyl ether, VC sodium phosphate, VC magnesium phosphate, VC ethyl ether, AA2G, VC-IP, etc.), kojic acid, UP302 (Dimethoxytolyl-4-propyl isophthalic acid) Phenol) and so on, they are all whitening ingredients without exception.
But the top whitening effect is Thiamidol, chemical name: Isobutyramidothiazolyl resorcinol; it is a derivative of resorcinol. Thiamidol became famous in the first battle with 7 masters (4-Butylresorcinol, hexylresorcinol, kojic acid, hydroquinone, arbutin, UP302), and is the strongest whitening ingredient on the surface.
The "second strongest on the surface" whitening ingredient is4-Butylresorcinol. Its whitening effect is 24 times stronger than kojic acid and 310 times stronger than arbutin.
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| Real shot pictures of Raw powder 4-Butylresorcinol | 4-Butylresorcinol structure diagram |
Product Application
1. Raw powder 4-Butylresorcinol has a strong inhibitory effect on tyrosinase and peroxidase.
2. It is an effective skin whitening agent and toner for normal skin.
3. It is an effective whitening agent for pigmented skin.
4. It can effectively fight chloasma.
5. It has a strong protective effect on DNA damage induced by H2O2.
6. It proved to have an anti-saccharification effect.
7. It can interfere with the synthesis and glycosylation of tyrosinase and prevent the enzyme from being absorbed by melanosomes.
8. It can inhibit the activity of enzymes, as a competitive inhibitor of tyrosinase and TRP1 enzyme, and reduce the formation of by-products that promote melanogenesis.
9. It can improve tyrosinase degradation, inhibit the transfer of melanosomes to keratinocytes, and has a photo stripping effect due to the action of fatty acids. This function is enhanced by the presence of fatty acids and regulates the degradation of tyrosinase.
Product Specification
Item | Specification | Results |
Identification | NMR/L-MS/HPLC | Conformed |
Appearance | White to off white powder | Conformed |
Resorcinol | ≤ 0.5% | 0.48% |
Total impurities | ≤ 1% | 0.61% |
Single impurity(max) | ≤ 1% | 0.5% |
Loss on dry | ≤ 0.5% | 0.3% |
Assay(HPLC) | ≥ 99% | 99.39% |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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