Tolnaftate Powder CAS 2398-96-1

Tolnaftate powder is a synthetic thiocarbamate, which is used as an antifungal agent. The molecular formula is C19H17NOS. We know that ergosterol is an important component of fungal cell membrane, which is very important for the growth and survival of fungi. Pure Tolnaftate ester is the earliest thiocarbamate antifungal agent on the market. It can inhibit squalene cyclooxygenase in the ergosterol synthesis pathway of fungi, resulting in the obstruction of ergosterol synthesis.

What is the comparison between Tolnaftate and Liranaftate?

Liranaftate powder is a squalene epoxidase inhibitor and a cell wall synthesis inhibitor. Its chemical structure is similar to that of Tolnaftate, and it is suitable for local treatment of skin fungal infections. Compared with tolnaphthyl ester, its mechanism of action is basically similar, that is, it inhibits the epoxidation of squalene in fungal cells. However, clinical evidence shows that liranaftate has stronger antifungal activity, which is 8 times that of Tolnaftate. If it is used in Aspergillus which is resistant to Tolnaftate, this product still maintains good sensitivity.
However, this product is not superior in all aspects, and its effect on most dimorphic fungi and yeasts is not ideal, which are also related to Tolnaftate. Besides antifungal effect, Tolnaftate also has certain anti-inflammatory and antipruritic effects. It can relieve the symptoms of skin itching and inflammation and make patients feel more comfortable.

What's the difference between Tolnaftate and Clotrimazole?

They are all antifungal products, but they are used in different ways. Tolnaftate powder is classified as a synthetic thiocarbonate. Clotrimazole is classified as an azole. Clotrimazole can be used in the vagina and mouth (according to regulations). Tinactin is only used for local application. Tolnaftate is unsafe for children, while Clotrimazole is safe for children. Tinactin can serve as a fungicide and also help prevent fungal infections. Clotrimazole is a strict fungicide.

Our company can provide various TOLNAFTATE, Liranaftate,Clotrimazole etc. If you are interested, please contact us via email:sales6@faithfulbio.com

What is the correct usage method of TOLNAFTATE?

Tinactin cream is an antifungal drug mainly used to treat diseases such as tinea manus, tinea pedis, and tinea corporis. Patients can apply this product to the affected area under the guidance of a doctor and gently massage until absorbed, which can effectively alleviate discomfort symptoms. However, it should be noted that if allergic to this product, it is not recommended to use this medicine to avoid adverse reactions such as skin itching and redness. In addition, during use, it is important to avoid contact with the eyes and other mucous membranes such as the mouth and nose to prevent irritation and injury.
In addition, patients should pay attention to maintaining local cleanliness and hygiene in daily life, frequently changing and washing shoes and socks, and avoiding sharing a pair of shoes with others. At the same time, we should also pay attention to reasonable diet, and try to focus on light and digestible food, such as millet gruel, pumpkin Congee, etc., and eat less spicy, greasy and cold food, such as pepper, fried chicken, ice cream, etc., to avoid aggravating the disease. If there is obvious discomfort during the period, it is necessary to seek medical treatment in a timely manner to avoid delaying the condition.

What are the antibacterial and insecticidal effects of Tinactin?

Tolnaftate powder has the effects and functions of anti malaria, anti amoebic disease, anti schistosomiasis, anti leprosy, anti filariasis, etc.

1. Tolnaftate exerts its anti malaria effect by interfering with the growth cycle of malaria parasites, preventing their reproduction in red blood cells.

2. Tolnaftate can effectively inhibit the growth and spread of amoebic protozoa, reduce inflammatory reactions, and alleviate symptoms.

3. Tolnaftate can effectively kill adult schistosomiasis and has a certain killing effect on the eggs.

4. Tolnaftate has the effect of inhibiting the proliferation of leprosy bacilli, which helps to control the progression of the disease.

5. Tolnaftate can disrupt the biofilm structure within the body of silk worms, leading to their death.

In addition, as Tinactin is a compound with a benzimidazole structure and relatively stable chemical properties, it is also an efficient and low toxicity insecticide widely used in agricultural production. The insecticidal activity of Tinactin is mainly reflected in its ability to effectively kill various pests, such as aphids, spider mites, borers, etc. At the same time, it can be converted into tannic acid salt under acidic conditions, which has stronger insecticidal activity. In addition, Tinactin also has certain systemic and gastric toxicity, which means that it can not only be absorbed by plant roots, but also directly act on the digestive system of pests, thereby achieving better insecticidal effects.
Although Tinactin has certain toxicity, its impact on humans and the environment is relatively small under normal use. Users only need to follow the safe use regulations of pesticides, take personal protective measures, and avoid direct contact with pesticides. At the same time, residual Tolnaftant also has certain impacts on soil and water sources, and needs to be used and disposed of reasonably.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Can provide you with a good price.Our company can provide various TOLNAFTATE, Liranaftate,Clotrimazole etc. If you are interested, please contact us

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