What is SEL12034A HCl?
SEL120-34A HCl appears as a white powder, CAS 1609452-30-3, The molecular formula is C15H19Br2ClN4, with a molecular weight of 450.59916. This product is an effective, selective, orally administered, ATP competitive CDK8 inhibitor.
Xi'an Faithful BioTech Co.,Ltd focuses on the research and development, production and sales of pharmaceutical intermediates and other chemical raw materials. We have been rooted in chemical raw materials for more than 10 years. There are a group of hard-working, motivated, and creative staff working not only for the company but also for you-our respectable customer and partner! Based on good service and high-quality products, we're widely praised and trusted by customers and keep long-lasting relationships with them.If you need to consult or order high-quality SEL120-34A HCl products, please contact us.
| Product name | SEL120-34A HCl |
| CAS | 1609452-30-3 |
| Molecular formula | C15H19Br2ClN4 |
| Molecular weight | 450.59916 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | -20°C |
| Appearance | White powder |
| boiling point | NA |
| Density | NA |
Product Specification
| Items | Specification | Results |
| Appearance | white powder | Complies |
| Purity(%) | ≥98% | 99.77% |
| Conclusion | Conform with enterprise specification . | |
Send your Inquiry for more details,Click email:sales2@faithfulbio.com or Whatsapp: +86 17782785148 Now.
Where is SEL12034A HCl used?
SEL120-34A HCl is mainly used in scientific research fields, especially in cancer-related research.
Cancer research: This product exhibits strong activity in malignant hematological tumors such as acute myeloid leukemia, acute lymphocytic leukemia, and mantle cell lymphoma, and can inhibit tumor cell proliferation and alter gene transcription programs related to leukemia cell differentiation.
Research on transcriptional regulation mechanism: This product inhibits CDK8/CDK19, which can block the phosphorylation of key sites of STAT1 and STAT5, thereby interfering with interferon signaling pathways and cytokine responses. It is a tool compound for analyzing transcriptional regulation and signaling pathways.
What are the effects of SEL12034A HCl?
SEL120-34A HCl has clear anti-tumor activity, and the core effects of this product are as follows:
Inhibition of CDK8/CDK19 kinase activity: The IC ₅₀ for CDK8/CycC is 4.4 nM, for CDK19/CycC is 10.4 nM, and the selectivity for CDK9 exceeds 200 times, with no significant inhibition on CDK1/2/4/5/6/7.
Blocking the STAT signaling pathway: By inhibiting the phosphorylation of STAT1 S727 and STAT5 S726 sites, interferon responsive genes and related transcription programs are regulated.
This product is a research tool medicine and cannot be used on the human body.
How and where to buy SEL12034A HCl wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL, Germany DHL, Germany DPD, UPS, USPS,FedEx, TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Send your Inquiry for more details,Click email:sales2@faithfulbio.com or Whatsapp: +86 17782785148 Now.
FAQ：
Q1:How can I trust you ?
A1:Our owner has over 10 years of experience in the chemical raw materials field as well as our staffs. It is because of the trust of our customers and partners that we have been able to exist and develop for so many years. Our ever-lasting vision is to 'Obtain a wide range of customer resources through high-quality procurement and the best service, and establish a sustainable and stable customer relationship'!
Q2:Is SEL120-34A HCl suitable for human consumption?
A2:No, this product is sold for laboratory research purposes only and is not intended for diagnostic, therapeutic, or household use.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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