Product Introduction
PGE2 powder is a white to off-white solid, Mp 64-66℃, specific rotation -61° (26℃, c=1, THF). It is easily hydrolyzed at pH<4 or pH>8. It is easily soluble in organic solvents such as chloroform, ethyl acetate, methanol, anhydrous ethanol, and slightly soluble in water. It is a natural prostaglandin (PG) that has a contraction effect on the uterus of all stages of pregnancy, but the sensitivity of the uterus of each stage of pregnancy to PGE2 is inconsistent, and the full-term uterus is the most sensitive. It can directly soften the cervix, which is conducive to cervical dilation. Dinoprostone can also cause gastrointestinal smooth muscle contraction and can also act on vascular smooth muscle.
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| PGE2 powder Picture | PGE2 powder MF |
Product Application
PGE2 powder is a uterine stimulant. It is the most biologically active prostaglandin that can induce cervical ripening and labor, mediate bradykinin-induced vasodilation, and regulate adenylate cyclase. Tumor cells overexpressing cyclooxygenase 2 have greater invasiveness, angiogenesis, and resistance to apoptosis, which may be due to PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein survivin. PGE2 has mixed effects on the immune system. It inhibits T cell activation in vitro, indicating that it is an immunosuppressant. However, in vivo, it affects the expansion of the Th17 subset and the differentiation of the Th1 subset of T helper cells, indicating that it is an immune activator. It is used for pregnancy induction of labor, mid-pregnancy induction of labor and therapeutic abortion, and preoperative cervical dilation.
The signaling pathway of PGE2. The schematic diagram shows the downstream signaling pathway of PGE2. The lipid mediator actives or inhibits the target cell via four EP receptors, EP1, EP2, EP3, and EP4. Different receptors activate different signaling pathways which are connected in a network in the cell and cooperate with each other in vital processes.
Prostaglandin E2 (PGE2) is a lipid mediator derived from the fatty acid arachidonic acid. As an essential inflammatory factor, PGE2 has a critical impact on immune regulation through the prostanoid E (EP) receptor pathway. T cells, including CD4⁺ and CD8⁺ T cell subsets, play crucial roles in the adaptive immune response.
Product Specification
| Item | Standard | Test Results |
| Appearance | White to off-white powder | Complies |
| Partical Size | 100% pass 80 mesh | Complies |
| Loss on Drying | ≤3.0% | 0.023 |
| Purity | >98.00% | 0.9845 |
| Total Heavy Metals | ≤10ppm | <10ppm |
| As | ≤1.0ppm | <0.1ppm |
| Pb | ≤1.0ppm | <0.2ppm |
| Cd | ≤0.5ppm | Negative |
| Hg | ≤1.0ppm | Negative |
| Total Plate Count | ≤1,000cfu/g | <15cfu/g |
| Mold and Yeast | ≤100cfu/g | <5cfu/g |
| E.Coli | ≤1cfu/g | 0.003cfu/g |
| Salmonella | ≤1cfu/g | Negative |
| Allergens | - | Negative |
| GMO | - | Negative |
| Residue of Pesticide | ≤1cfu/g | Negative |
| Part used | Coptis chinensis | Rhizome |
| Conform with the enterprise standard |
How To Obtain Samples PGE2 powder?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API PGE2 powder.
The Best PGE2 powder Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio PGE2 powder?
Faithfulbio specialize in PGE2 powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use PGE2 powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy PGE2 powder?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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