Obeticholic Acid Powder CAS 459789-99-2

Name: Obeticholic Acid Powder CAS 459789-99-2
Brand: Faithful
SKU: 248889870

Product Name:Obeticholic Acid
Synonym:Nexium;6-Ethylchenodeoxycholic aicd;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph
CAS NO.:459789-99-2
EINECS NO.:810-245-2
Molecular Formula:C26H44O4
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months

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Description

Product description

Obeticholic Acid Powder, also known as 6-ethyl goosenodeoxycholic acid, is a novel derivative of Chenodeoxycholic acid (CDCA) in human primary bile acids and a natural ligand for farnesate derivative X receptor (FXR). Obecholic acid is a farnesol X receptor agonist, which indirectly inhibits cytochrome 7A1 (CYP7A1) gene expression by activating farnesol X receptor. Because CYP7A1 is a rate-limiting enzyme for cholic acid biosynthesis, obecholic acid can inhibit cholic acid synthesis and is used in the treatment of primary biliary cirrhosis and non-alcoholic fatty liver disease.

PBC is a chronic cholestasis caused by bile duct dysplasia or bile acid metabolism disorder, which causes lipid dissolution of cell membrane, permeability change, cell content flow out, and eventually progress to liver fibrosis and cirrhosis. At present, ursodeoxycholic acid is the main drug used in clinical treatment of PBC. Ursodeoxycholic acid stimulates hepatobiliary secretion through intracellular signaling molecule mitogen-activated protein kinase (MAPK) pathway, and protects epithelial cells from bile acid destruction.

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ltems	Standard	Results
APPEARANCE	Off white to white powder	White powder
IDENTIFICATION	A: IR B: Retention time	Complies Complies
WATER	≤0.5%	0.06%
HEAVY METALS	≤0.002%	Complies
ISOMERS	SFBD1≤0.15%	Undetected
	SFBD2≤0.15%	Undetected
	SFBE≤0.15%	Undetected
RESIDUE SOLBENTS	Methanol≤3000ppm	Undetected
	Isopropyl alcohol≤5000ppm	19ppm
	Dichloromethane≤600ppm	Undetected
	Tetrahydrofuran≤720ppm	Undetected
	Acetic acid≤5000ppm	Undetected
	Toluene≤890ppm	Undetected
ASSAY	≥99%	99.80%
Conclusion:	Conform with enterprise specification.

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How safe is obeticholic acid?

OCA is contraindicated for patients with complete biliary obstruction. Obeticholic acid is also contraindicated for patients with decompensated cirrhosis (eg, Child-Pugh class B or C) or compensated cirrhosis with evidence of portal hypertension, such as gastroesophageal varices, ascites, or ongoing thrombocytopenia.

What is another name for obeticholic acid?

Obeticholic Acid Powder (OCA), is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It is used as a medication used to treat primary biliary cholangitis.

What is the generic for obeticholic acid?

It can be used alone or with another medication called ursodiol. There's currently no available generic version of obeticholic acid. Common side effects include itchiness, fatigue, and stomach pain, but it also has a warning for liver problems.

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We adhere to the principle of "customer first, honesty first", and always provide customers with high-quality and efficient products and high-quality services. Choose faithfulness. Choose a healthy life!

With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.

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Transportation Time	Shipping method	Cargo weight requirements	Advantage
3-7 days	DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS	Suitable for under 50kg. International door to door express	We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.
7-15 days	By Air	Suitable for more than 50kg. fast and cheaper for large order
15-60 days	By Sea	Suitable for more than 500kg. Cheapest shipping way

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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.

Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.

Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

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