Tobramycin Powder CAS 32986-56-4

Tobramycin Powder is also known as Tobramycin. One of the aminoglycoside antibiotics. It is produced by Streptomycestenebrarius. It's usually sulfate. The antibacterial spectrum was similar to that of gentamicin, but the antibacterial force against Pseudomonasaeruginosa was 2 to 4 times stronger, and it was also effective against gentamicin-resistant strains. The antibacterial activity against other G-bacilli is slightly inferior to gentamicin. It can be used to treat a variety of serious infections caused by Pseudomonas aeruginosa and other G-bacilli, but is generally not used as a drug of choice. Tobramycin, an aminoglycoside antibiotic with less clinical resistance, is used as a first-line treatment for early pulmonary infection with Pseudomonas aeruginosa.

The minimum inhibitory concentration of this product against most of the pseudomonas aeruginosa is less than 1.5μg/ml, and the minimum inhibitory concentration against most of the Escherichia coli, pneumococcus, Enterobacter mirabilis, Proteus mirabilis, citrobacter and acinetobacter is less than 1.5μg/ml. The sensitivity of Staphylococcus to tobramycin and gentamicin is roughly the same, and the minimum inhibitory concentration for most Staphylococcus aureus is less than 1μg/ml. The effect of this product on enterococcus is very weak, and its minimum inhibitory concentration is ≥25μg/ml. The minimum inhibitory concentration for pneumococcus, green streptococcus and streptococcus pyogenes was often greater than 25μg/ml. There was incomplete cross-resistance between tobramycin and gentamicin.