Cisapride Powder CAS 81098-60-4

Cisapride is a benzamide based gastrointestinal motility product that can enhance and coordinate gastrointestinal movement, prevent food retention and reflux, and therefore has antiemetic effects. Pure Cisapride powder is a white solid with strong sedative effects and can also be used as a treatment for mental illness.

Can cisapride tablets and omeprazole be used together?

Cisapride tablets are a product that improves gastrointestinal motility and can be used to treat functional dyspepsia, mild reflux esophagitis, and other diseases. Omeprazole is an acid suppressant that can be used to treat gastric ulcers, reflux esophagitis, duodenal ulcers, and combined with antibiotics to treat Helicobacter pylori infection. Cisapride and omeprazole can not only be taken simultaneously, but if taken before meals, it can reduce the impact of food factors on the medication and have better efficacy. Our recommendation is to take them orally 15-30 minutes before meals.

Our company can provide you with Cisapride, Omeprazole, Domperidone and Mosapride at a better price. If you are interested, please contact us by email:sales6@faithfulbio.com

What's the difference between Cisapride and Mosapride?

1. The essence of the drugs is different: although both belong to drugs that promote gastrointestinal peristalsis, the essence of the cisapride powder is a benzamide derivative, while the essence of the mosapride powder belongs to a 5-hydroxytryptamine 4 receptor agonist.
2. The specific functions are different: the main component of cisapride preparations is cisapride, which can promote local gastrointestinal motility and prevent symptoms such as food reflux and food stasis. The main ingredient of mosapride preparations is mosapride, which can relieve symptoms such as abdominal pain, nausea and vomiting, bloating, and local burning sensation.
3. Different diseases are treated: cisapride formula is mainly applicable to functional dyspepsia, upper gastrointestinal discomfort, gastroesophageal reflux disease, etc. In addition to diabetes gastroparesis, it also has a good effect on gastric paralysis caused by local trauma, excessive mental pressure, and pseudo intestinal obstruction. Mosapride formula is mainly used to treat dysfunction caused by gastrectomy, diabetes gastroparesis, reflux esophagitis and other diseases.
4. Different sites of action: At the same time, cisapride are full gastrointestinal motility drugs that can cause peristalsis in the entire digestive tract, but Mosapride have higher selectivity for the upper gastrointestinal tract and cannot cause colonic peristalsis.
5. Adverse reactions: Cisapride may cause cardiovascular system adverse reactions, such as QT interval prolongation, apical torsion type ventricular tachycardia, etc., and may even lead to death. Mosapride has relatively high cardiac safety, but it can also cause adverse reactions such as QT interval prolongation.
In addition to the above adverse reactions, there are also some common side effects between the two, such as mild nausea and vomiting. If you experience related symptoms, you should let your doctor know and adjust the use of the product with their help. At the same time, you should promptly observe whether there are allergies, liver and kidney dysfunction, and other conditions.

Which is more effective, cisapride or Domperidone?

Cisapride powder is a gastrointestinal motility drug, and its mechanism of action is different from other common gastrointestinal motility drugs such as metoclopramide and domperidone. It does not affect dopamine receptors, but selectively acts on the postganglionic endings of the intermuscular plexus in the gastrointestinal tract, blocking the degradation of acetylcholine by neurons and promoting its release (time and quantity), thereby stimulating the entire gastrointestinal tract to exert a prokinetic effect. After use, cisapride does not inhibit acetylcholinesterase activity, has no dopamine receptor blocking effect, does not increase gastric acid secretion, and does not affect plasma prolactin levels.
domperidone powder can block the action of dopamine in the emetic chemosensory zone and inhibit the occurrence of vomiting; It can promote the normal recovery of peristalsis and tension in the upper gastrointestinal tract, and accelerate postprandial gastric emptying. In addition, it can also enhance the tension of the cardiac sphincter and promote the expansion of postprandial peristalsis of the pyloric sphincter. After use, this product does not affect the secretion of gastric juice. Due to its weak passage through the blood-brain barrier, it does not have significant sedative, drowsy, or extrapyramidal side effects.
Overall, the mechanisms of action of the two products are completely different, so their manifestations may vary depending on the symptoms and conditions. However, domperidone is a second-generation gastrointestinal motility promoting drug, and Cisapride is a third-generation gastrointestinal motility promoting drug, with higher bioavailability and longer lasting efficacy than Domperidone. Patients should choose according to their own symptoms and the doctor's advice when using it. Meanwhile, during use, patients should pay attention to observing their own reactions and seek medical attention promptly if they experience discomfort.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide low-priced Cisapride, Omeprazole,Domperidone and Mosapride for your research and comparison. If you have relevant purchasing plans, please contact us

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