What is Bromhexine hydrochloride?
Bromhexine hydrochloride is a dissolving agent for phlegm, which can directly act on bronchial glands, promote the release of lysosomes of mucus-secreting cells, differentiate and crack mucopolysaccharide fibers in sputum, dilute sputum and cough up easily.
Bromhexine hydrochloride powder is a white crystalline powder, which is a common organic compound. Melting point is 237-238℃ (decomposition). Slightly soluble in water, ethanol and methanol, slightly soluble in hot ethanol, insoluble in acetone and chloroform, odorless and tasteless. Bromhexine hydrochloride is a semi-synthetic duckweed derivative, which is an expectorant and has a strong effect on dissolving phlegm.
| Product name | Bromhexine hydrochloride |
| CAS | 611-75-6 |
| Molecular formula | C14H21Br2ClN2 |
| Molecular weight | 412.59 |
| EINECS Number | 210-280-8 |
| Storage condition | Sealed in dry,Room Temperature |
| Melting point | 240-244 °C |
| Solubility | Very slightly soluble in water, slightly soluble in ethanol and dichloromethane. |
| Appearance | White to light beige powder |
| Boiling point | 441.5 oC at 760 mmHg |
| Density | 1.51±0.1 g/cm3(Predicted) |
What is the pharmacological action of Bromhexine hydrochloride?
Bromhexine hydrochloride powder has a strong effect of dissolving mucus and mucus, which can break down the polysaccharide cellulose in sputum and dilute the sputum. It inhibits the synthesis of glycoproteins in goblet cells and mucous glands, reduces the sialic acid in sputum, reduces the viscosity of sputum, and facilitates coughing.
The expectorant effect of Bromhexine hydrochloride is related to its promotion of ciliary movement of respiratory mucosa and its nauseating expectorant effect.
Product Specification
| Item | Specification | Results |
| Appearance | White or almost white crystalline powder | Conforms |
| Identification | HNMR and HPLC retention time. | Positive |
| Sieve analysis | 100% pass 80 mesh | Conforms |
| Related Substances | ≤0.50% | 0.25% |
| Loss On Drying | ≤1.0% | 0.80% |
| Sulphated Ash | ≤0.5% | 0.40% |
| Content | 98.5~100.5% | 99.70% |
| Conclusion: | Conform with enterprise specification. |
What are the effects of bromhexine hydrochloride?
The efficacy and effects of bromhexine hydrochloride powder generally include decomposing sputum protein, reducing sputum viscosity, inhibiting inflammation, improving airway patency, regulating immunity, etc.
1. Decomposing sputum protein:
Bromhexine hydrochloride can decompose the protein in sputum, making the sputum thinner and easier to cough up.
2. Reducing sputum viscosity:
This product can inhibit the synthesis of glycoproteins by goblet cells and mucous glands, reduce sialic acid in sputum, reduce the viscosity of sputum, and facilitate coughing.
3. Inhibiting inflammation:
Bromhexine hydrochloride has an anti-inflammatory effect and can alleviate the symptoms of inflammatory lesions.
4. Improving airway patency:
Bromhexine hydrochloride helps keep the airway patency and prevent airway obstruction.
5. Regulating immunity:
Bromhexine hydrochloride also has an immunomodulatory effect, which helps to improve the body's resistance.
HTML5 atlas of Bromhexine hydrochloride
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What are the differences between bromhexine hydrochloride and ambroxol hydrochloride?
1. Different product composition: The main ingredients of bromhexine hcl and ambroxol hydrochloride are different. The main ingredient of bromhexine hcl is bromhexine hydrochloride powder. The main ingredients of ambroxol are ambroxol hydrochloride, bromhexine active metabolites, etc.
2. Different scope of use: Bromhexine hydrochloride is mainly used to treat increased sputum caused by gray tract diseases, which can improve bronchitis, asthma, etc. Ambroxol hydrochloride is mainly used to treat pneumonia and other diseases.
3. Different reactions: Bromhexine hydrochloride drugs cause adverse reactions, which may cause symptoms such as nausea and vomiting. Ambroxol hydrochloride causes adverse reactions, which may cause indigestion, urticaria and other symptoms.
What are the precautions for Bromhexine hydrochloride powder?
1. Bromhexine hydrochloride is irritating to the gastrointestinal mucosa. Patients with gastritis or gastric ulcer should use it with caution.
2. Patients with impaired liver function should use it under the guidance of a physician.
3. Patients who are allergic to bromhexine hydrochloride are prohibited from using it. Those with allergic constitutions should use it with caution.
4. Bromhexine hydrochloride is prohibited from use when its properties change.
How and where to buy Bromhexine Hydrochloride Powder wholesale?
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure, or prevent any disease.
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