Product description
Indobufen CAS 63610-08-2 is a highly selective antiplatelet aggregation product. Its clinical application focuses primarily on its antiplatelet effect, with weaker antipyretic, analgesic, and anti-inflammatory effects. Due to its low bleeding risk and good tolerability, it has become a commonly used product for the prevention and treatment of thrombotic diseases in clinical practice, and is also an important raw material in the pharmaceutical and chemical industries.
Indobufen inhibits platelet aggregation through a dual mechanism, and its highly selective effect on vascular endothelial cells is key to its differentiation from traditional antiplatelet products such as Acetylsalicylic acid: It reversibly inhibits platelet cyclooxygenase-1 (COX-1), reducing the production of thromboxane A₂ (TXA₂) (TXA₂ is a core mediator of platelet aggregation and vasoconstriction); and it inhibits the release of platelet-promoting substances such as ADP, serotonin, and platelet factors, blocking the chain reaction of platelet adhesion and activation.
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COA
| Tests | Specifications | Results |
| Appearance | White or almost white crystalline | Conforms |
| Loss on drying | ≤0.5% | 0.03% |
| Ash | ≤0.1% | 0.04% |
| Heavy metals | ≤20 ppm | <20 ppm |
| Lead(Pb) | ≤0.5ppm | ≤0.5 ppm |
| Arsenic(As) | ≤0.5 ppm | <0.5 ppm |
| Mercury(Hg) | ≤0.5 ppm | <0.5 ppm |
| Cadmium(Cd) | ≤0.5 ppm | ≤0.5 ppm |
| Total Plate Count | ≤1,000 cfu/g | Conforms |
| Yeasts&Molds | ≤100 cfu/g | Conforms |
| E.Coli | ≤3.0 mpn/g | Negative |
| Salmonella | Negative | Negative |
| Conclusion | Conform with enterprise specification | |
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Density: 1.3±0.1 g/cm³
Boiling point: 518.1±50.0 °C at 760 mmHg
Melting point: 33-34 °C (lit.)
Molecular formula: C18H17NO3
Molecular weight: 295.33
Flash point: 267.1±30.1 °C
Exact mass: 295.120850
PSA: 57.61000
LogP: 3.30
Indications for Indobufen CAS 63610-08-2
Primarily used for the prevention and treatment of platelet aggregation-related thrombotic diseases, clinical applications include:
Ischemic cerebrovascular diseases: secondary prevention and adjuvant therapy in the acute phase of cerebral infarction and transient ischemic attack (TIA);
Cardiovascular diseases: antiplatelet therapy for coronary artery disease (stable angina, non-ST-segment elevation myocardial infarction) and after coronary stent placement;
Peripheral vascular diseases: prevention and treatment of lower extremity arteriosclerosis obliterans and thrombophlebitis;
Postoperative thrombosis prevention: prevention of deep vein thrombosis and pulmonary embolism after major surgeries such as orthopedic and general surgery;
Others: prevention of thrombosis in dialyzer and vascular access in hemodialysis patients.
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why choose us
Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What are the common adverse reactions of Indobufen CAS 63610-08-2, and are they serious?
Adverse reactions are infrequent and mostly mild to moderate, resolving spontaneously upon discontinuation of use: ① The most common are gastrointestinal reactions (mild abdominal pain, nausea, indigestion, bloating); ② Occasionally, bleeding tendencies (skin ecchymosis, nosebleeds, gum bleeding); ③ Other occasional reactions include dizziness and fatigue, and rarely, skin rash or transient abnormalities in liver and kidney function.
02. In international shipping, if Indobufen CAS 63610-08-2 is delayed due to customs inspection, will this affect product quality?
If the goods are sealed and protected from light throughout the delay, and the temperature and humidity are below 25℃/60% RH, short-term delays will not affect product quality. If the temperature and humidity exceed the standards during the delay, a quality re-inspection must be conducted immediately after the goods are received into the warehouse to confirm whether the content, related substances, and other indicators meet the standards.
03. Where can I buy Indobufen CAS 63610-08-2?
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