what is Oleoyl Ethanolamide powder?
Oleoyl Ethanolamide powder appears as a white solid. It is an agonist of peroxisome proliferator activated receptor alpha (PPAR - α) and a selective GPR55 agonist. Oleoyl Ethanolamide produces intestinal signals that stimulate central dopamine activity, establishing connections between calorie self balance and pleasure self balance. Oleoyl ethanolamide is considered the molecular mechanism underlying the success of gastric bypass surgery.
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Product name |
Oleoyl Ethanolamide |
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CAS |
111-58-0 |
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Molecular formula |
C20H39NO2 | |
| EINECS |
203-884-8 |
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Molecular weight |
325.53 | |
| Melting point | 63-64 °C | |
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Density |
0.915±0.06 g/cm3(Predicted) | |
| Appearance | White powder |
What are the main uses of Oleoyl Ethanolamide powder?
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The main functions of Oleoyl Ethanolamide Powder are:
Oleoyl Ethanolamide is an important food intake inhibitory factor, whose main function is to help alleviate obesity. The weight loss effect of Oleoyl Ethanolamide is mainly that it can induce satiety, thereby controlling excessive food intake. Adding a certain concentration of OEA to the feed of normal or obese mice can reduce their appetite and weight. |
- Lower blood lipids
Peroxisome proliferator activated receptor - α (PPAR - α) is a kind of receptor closely related to metabolic function in the body. PPAR - α plays a role in regulating blood lipids and anti atherosclerosis by combining with peroxisome proliferator response elements and participating in lipid metabolism transport, immune regulation, anti-inflammatory, anti proliferation and other related processes.
Research shows that Oleoyl Ethanolamide can activate PPAR-M, reduce the release of Endophyllin-1 (human, protein), inhibit vascular contraction and smooth muscle cell proliferation, promote vascular relaxation, and increase the synthesis of endothelial nitric oxide synthesis, induce more NITRIC OXIDE, thereby reducing the production of vascular cell adhesion molecules, achieving anti-inflammatory effects, playing a role in lowering blood lipids and anti atherosclerosis.If you need it, pls click e-mail: sales1@faithfulbio.com.
Product Specification
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Item |
Specification |
Result |
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Assay(%,On Dried Base) |
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N-(2-Hydroxyethyl)-9-Z-octadecenamide |
>87.0% |
87.80% |
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Palmitoyl Ethanolamide |
<5.0% |
4.46% |
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- hydroxyethyl) - Octadecadienamide, |
<4.0% |
3.60% |
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N-(2-Hydroxyethyl)-Octadecanamide |
<3.0% |
2.65% |
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others acid's hydroxyethyl amides |
<1.0% |
0.80% |
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Physical Control |
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Appearance |
Fine Flake |
Complies |
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Color |
White to Off white |
Complies |
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Identification |
Positive |
Complies |
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Loss on Drying |
1.0% Max |
0.48% |
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Residue on ignition |
0.10% Max |
0.04% |
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Chemical Control |
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Heavy metals |
NMT10PPM |
Complies |
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Arsenic(As2O3) |
NMT1PPM |
Complies |
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Sulfate(SO4) |
NMT 0.020% |
Complies |
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Iron(Fe) |
NMT10PPM |
Complies |
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Chloride(Cl) |
NMT 0.020% |
Complies |
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Solvents Residual |
Meeting USP Standard |
Complies |
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Microbiological Control |
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Total Plate Count |
10,000cfu/g Max |
Complies |
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Yeast & Mold |
300cfu/g Max |
Complies |
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Coliforms |
10cfu/g Max |
Complies |
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E.Coli |
Negative/10g |
Complies |
|
Salmonella sp. |
Negative/25g |
Complies |
|
Staph Aureus |
Negative/10g |
Complies |
|
Pseudomonas aeruginosa |
Negative/25g |
Complies |
| Conclusion： Conform with enterprise specification . | ||
How to synthesize Oleoyl Ethanolamide powder?
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Add 100 mL of Dichloromethane (DCM) and 2.3 mL of Triethylamine (16.62 mmol) to 5.0 g Monoethanolamine (16.62 mmol) to prepare a reaction solution. Reduce the temperature of the reaction solution to 0 ℃ using the ice bath method, and slowly add 13.8 mL of oil chlorine(CH3(CH2)7CH = CH(CH2)7COCl, 0.1 mol), Stir at room temperature for 4 hours. After stirring, add 150ml of water, extract the resulting solution with 150ml of ethyl acetate, and wash the organic layer with 150ml of saline solution. Collect all organic layers and dry them on sodium sulfate. The filtered filtrate is subjected to rotary evaporation to remove the solvent. Wash the residue with Hexane to obtain 5.27 g of white solid - Oleoyl Ethanolamide powder with a yield of 97%. |
How and where to Buy Oleoyl Ethanolamide powder?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
FAQ
Q:What foods contain Oleoyl Ethanolamide?
A:It is widely present in animal and plant tissues such as cocoa powder, soybeans, and nuts, but its content is extremely low.
Q:How Oleoyl Ethanolamide powder packaged?
A:We usually pack it in a sterile bag, which has two layers of aluminum foil bags outside.The bulk will be packed in cardboard drums.
Q:How long it will take for shipping?
A:It usually take 8-15 work days shipping to most region.
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
Send your Inquiry for more details, Click email：sales1@faithfulbio.com Now.
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