Product introduction
Xi'an Faithful BioTech Co., Ltd. is one of the most reliable API powder manufacturers and suppliers in China. We have rich experience in foreign trade, both in transportation and service. We warmly welcome you to wholesale bulk Erdafitinib API Raw Material from our factory. We have high-quality products and competitive prices.
Basic physical and chemical properties of Erdafitinib API Raw Material
Erdafitinib API Raw Material is a small molecule organic compound, which belongs to the main component of effective finished drugs. The appearance of pharmaceutical-grade tinib raw material is "pale yellow to yellow solid powder", and its water solubility is poor. Laboratory research shows that it is almost insoluble in pure water, but it can be dissolved in some organic solvents.
We will be curious about how it is different from other products. It can inhibit four receptor subtypes of FGFR1, FGFR2, FGFR3 and FGFR4 at the same time, which is the core feature that distinguishes it from other FGFR targeted products.
The purity of raw materials is the primary index of procurement. Pharmaceutical API requires HPLC purity ≥98.%, and all kinds of impurities, including residual solvents and heavy metals, need to be strictly controlled. The purity and quality of our products have passed the inspection, and we can provide you with the COA analysis certificate and HPLC chromatogram of the same batch of products.
| Product name | Erdafitinib API raw material |
| CAS | 1346242-81-6 |
| Molecular formula | C25H30N6O2 |
| Molecular weight | 446.54 |
| Melting point | 136-140 C |
| Density | 1.20 0.1g/cm3 (predicted) |
Small molecule chemical synthesis API
According to the classification of raw materials and drugs, Erdafitinib API Raw Material belongs to small molecule chemical synthesis API, and the molecule has no chiral center, so there is no complicated chiral isomer resolution problem. Stable physical and chemical properties, low hygroscopicity and controllable crystal form.
We focus on the process development and whole-chain quality research of this variety, and can provide the research and development of small-scale, pilot-scale and GMP commercial batches of APIs, and support the research data of COA, MSDS and impurities.
Product Specification
| Items | Specifications | Results |
| Appearance | Yellow solid | Yellow solid |
| Assay (HPLC) | ≥98.5% | 99.4% |
| NMR | Conforms to structure | Conforms |
| Infrared Spectrum | Conforms to structure | Conforms |
| Conclusion: The test results are conformed to the in-house specification | ||
What is the action mechanism of Erdafitinib API Raw Material ?
Erdafitinib API Raw Material is a pan-FGFR tyrosine kinase inhibitor. When tumor cells mutate, fuse or expand, these receptors are like stuck switches, constantly sending out proliferation signals, activating downstream pathways and promoting tumor growth and spread. As a space-occupying blocker, his molecules seize the energy binding site on the receptor, cut off abnormal signal transmission, inhibit tumor cell proliferation and induce cancer cell apoptosis.
It is different from inhibitors that only target a single subtype, and it can act on multiple types at the same time, covering more types of gene mutations. Erdafitinib is only effective on FGFR susceptible tumors, and it is targeted to target cells.
Process core advantage
1. Stable crystal form:
There is no risk of polymorph, which saves the screening time and research and development cost of preparation customers;
2. Low impurity level:
The purification process is optimized directionally, and the control of genotoxic impurities and process impurities is better than the limited threshold;
3. Flexible batch delivery:
Gram-level research and development samples, 10-gram-level clinical batches and kilogram-level commercial batches can all be supplied;
4. Green process:
Optimize the solvent system, reduce the use of highly toxic solvents, and improve the three wastes treatment plan to meet the global environmental protection standards;
Erdafitinib API Raw Material 's trusted supplier
We have nearly 10 years of product production experience and foreign trade export experience, equipped with professional business team, R&D and quality inspection team, which can stably control the quality of products and provide them to customers at the factory direct price, and have outstanding advantages in production capacity and cost. Regular categories are in stock, which effectively guarantees the delivery time.
Our factory mainly deals in API powder, plant extract powder, etc., and always puts quality first. Over the years, it has served tens of thousands of customers and gained wide recognition. We pursue long-term and stable partnership, and rely on strict quality control system and competitive pricing to reduce customer procurement costs. In order to further reduce the logistics cycle and cost of customers, we set up two overseas warehouses in Germany and the United States to support direct delivery and safe customs clearance of overseas warehouses.
Send your Inquiry for more details , Clicke mail：sales7@faithfulbio.comOr WhatsApp: +8617791967496
A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL, Germany DHL, UPS, USPS, FedEx, TNT, EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-40 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
If you need it, Click email：sales7@faithfulbio.com Or WhatsApp: +8617791967496
FAQ:
Q1:Does erdafitinib make you taller?
A1:Erdatinib is designed to inhibit the abnormally activated FGFR pathway in tumors, not growth hormone. At present, there is no research showing that it can promote bone growth and increase.
Q2:Is erdafitinib worth it ?
A2:The latest experimental results of the medical doctor of the University of Texas Cancer Center confirm that erdafitinib can benefit patients with advanced bladder cancer, whose tumors have one of the four FGFR genes changed.
Q3: Is the Erdafitinib API in stock? How long is the delivery cycle ?
A3:Regular inventory has spot samples and batch raw materials, and spot orders can be quickly arranged for delivery; If you need to customize the production batch, we will confirm the production cycle separately.
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Attention:
It cannot be used for the diagnosis, treatment, radical cure or prevention of any disease. This compound is only for scientific research purposes, and direct use is strictly prohibited. Please consult a professional doctor and consult relevant research literature before use
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