Chlorpheniramine Maleate Powder CAS 113-92-8

Chlorpheniramine Maleate Powder CAS 113-92-8

Product Name:Chlorpheniramine maleate powder;Chlorpheniramine maleate
CAS NO.:113-92-8
Molecular Formula:C20H23ClN2O4
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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Description

Product Introduction

Chlorpheniramine maleate powder, white crystalline powder. Melting point 131-135℃. Soluble in water, ethanol, chloroform, slightly soluble in ether, odorless, bitter. Used for allergic rhinitis, colds and sinusitis, and allergic skin diseases such as urticaria, allergic drug eruptions or eczema, angioedema, and skin itching caused by insect bites.

Chlorpheniramine maleate powder Picture

Chlorpheniramine maleate powder MF

Chlorpheniramine maleate powder Picture Chlorpheniramine maleate powder MF

 

Product Application

Chlorpheniramine maleate powder is used for colds and skin and mucosal allergic diseases. It mainly treats urticaria, eczema, dermatitis, drug eruption, pruritus, neurodermatitis, insect bites, solar dermatitis, and can also be used for allergic dermatitis, vasomotor rhinitis, drug and food allergies, etc. In addition to having a strong competitive blocking effect on histamine H1 receptors on allergic target cells and playing an anti-allergic role by antagonizing H1 receptors, it also has an anti-M cholinergic receptor effect. Therefore, after taking the medicine, symptoms such as dry mouth, constipation, thickened sputum, and dry nasal mucosa may occur.

 

 

Chlorpheniramine maleate powder HPLC1

Obtained by two-step condensation of 2-p-chlorobenzylpyridine. Add sodium ammonia and anhydrous toluene to a dry reaction pot, heat to reflux, and drop 2-p-chlorobenzylpyridine and bromoacetaldehyde diethyl acetal at the same time. After addition, reflux reaction for 8 hours. Cool and let stand, take the toluene solution, dissolve the solid with a small amount of water and extract with toluene. Combine the extract with the toluene solution, wash with water until neutral, recover toluene, and obtain 3-p-chlorobenzene-3-(2-pyridyl)-propionaldehyde diethyl acetal.

Mix it with DMF and add it to the reaction pot, and add a mixture of formic acid and water under stirring. Heat to 110-120℃ for reaction for 2h, and 150-160℃ for reaction for 3h. Cool, recover DMF under reduced pressure, dilute with hot water, and adjust to pH14 with alkali solution. Then extract with toluene, wash the extract with water until neutral, recover toluene and distill under reduced pressure, collect the 150-190℃ fraction to obtain chlortrimetone.

Chlorpheniramine maleate powder structure1

 

Product Specification

Item Specification Result
Assay 98% 99.54%
Appearance white crystalline powder conforms
Odor Characteristic conforms
Taste Characteristic conforms
Particle Size NLT 100% Through 80 mesh conforms
Loss on Drying <2.0% 0.46%
Heavy metals
Total Heavy Metals ≤10ppm conforms
Arsenic ≤3ppm conforms
Lead ≤3ppm conforms
Microbiological Tests
Total Plate Count ≤1000cfu/g conforms
Total Yeast & Mold ≤100cfu/g conforms
E.Coli Negative Negative
Salmonella Negative Negative
Conclusion Conform with the enterprise standard

 

How To Obtain Samples Chlorpheniramine maleate powder?

Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Chlorpheniramine maleate powder.

 

The Best Chlorpheniramine maleate powder Manufacturer And Supplier

Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.

We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.

 

Why Choose Faithfulbio Chlorpheniramine maleate powder?

Faithfulbio specialize in Chlorpheniramine maleate powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.

 

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A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

kindly note: Use Chlorpheniramine maleate powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.

 

Where To Buy Chlorpheniramine maleate powder?

Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!

 

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