Elacestrant HCl CAS 1349723-93-8
Product:Elacestrant HCl;Elacestrant dihydrochloride;RAD1901 dihydrochloride;RAD-1901
CAS NO.: 1349723-93-8
Molecular formula:C30H40Cl2N2O2
Purity & Grade: 99% HPLC; Food grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 36 months
Lead Time: about 3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is Elacestrant HCl?
Elacestrant HCl is a selective ER degrading agent with oral activity. Its IC50 values for ER α and ER β are 48 and 870 nM, respectively. It can also effectively inhibit the growth of ER+breast cancer cell line in vivo and in vitro.
| Product name | Elacestrant HCl |
| CAS | 1349723-93-8 |
| Molecular formula | C30H40Cl2N2O2 |
| Molecular weight | 531.5568 |
| EINECS Number | 215-871-3 |
| melting point | NA |
| solubility | NA |
| Storage conditions | NA |
| Appearance | White powder |
| boiling point | NA |
| Density | NA |
Product Specification
| Item | Specification | Results |
| Assay(%,on dried base) | NLT 98.0% | 99.51% |
| Appearance | White powder | Conforms |
| Loss on Drying | NMT 5.0% | 0.13% |
| Residue on ignition | NMT 1.0% | 0.10% |
| Heavy Metals | NMT 10ppm | Conforms |
| Lead (Pb) | NMT 1.0ppm | Conforms |
| Arsenic (As) | NMT 1.0ppm | Conforms |
| Cadmium (Cd) | NMT 1.0ppm | Conforms |
| Mercury (Hg) | NMT 0. 1ppm | Conforms |
| Total Plate Count | NMT 1000cfu/g | Conforms |
| Yeast & Mold | NMT 100cfu/g | Conforms |
| Conclusion | Conform with enterprise specification | |
Where is Elacestrant HCl usually used?
Elacestrant HCl is mainly used for the treatment of breast cancer, and its specific applications include:
In vitro study: it can effectively inhibit the growth of ER+breast cancer cell line in vitro. It can also inhibit the expression of ER α and the proliferation of ER positive MCF-7 cells stimulated by estradiol (E2) in a concentration dependent manner.
In vivo research: It has a strong and profound inhibitory effect on tumor growth. In addition, it can preserve the bone loss caused by oophorectomy and prevent the uterine promoting effect of E2.
To sum up, it is mainly used in the research and treatment of breast cancer.
What are the effects of Elacestrant HCl?
Elaestrant HCl is an effective antagonist of ER positive breast cancer cell proliferation.
At the same time, it inhibits the expression of estrogen receptor protein and reduces the expression of progesterone receptor in MCF7, T47D, and HCC1428 cell lines. In summary, it exhibits significant anti-tumor activity both in vitro and in vivo. These effects make it a potential drug to treat breast cancer.
Please use this product under the guidance of a doctor and do not blindly use it.
How and where to buy Elacestrant HCl wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:Are you manufacturer or trading company?
A1:We are manufacturer and trader.
Q2:How to confirm the product quality before place an order?
A2:We can provide you with sample .Also we have the inspection report issued by the authoritative third- party testing agency.
Q3:Do you provide after sales service?
A3:We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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