Chloroquine Phosphate Powder CAS 50-63-5

Chloroquine phosphate belongs to the 4-aminoquinoline class of antimalarial drugs, which can inhibit the nucleic acid synthesis of malaria parasite schizonts, interfere with the growth and reproduction of malaria parasites, and have a highly effective killing effect on the red phase schizonts of malaria parasites. Pure Chloroquine diphosphate powder is a white solid that is soluble in water.

How is the clinical use of chloroquine phosphate?

1. Main functions: Malaria is a parasitic disease transmitted by mosquitoes, which is still a serious public health problem in the world, especially in tropical and subtropical regions.

The main component of chloroquine phosphate tablets is Chloroquine diphosphate, which can interfere with the reproduction of plasmodium and form a complex with DNA, thus preventing DNA replication and RNA transcription. Chloroquine can also inhibit the incorporation of phosphoric acid into the DNA and RNA of plasmodium, which interferes with the reproduction of plasmodium because of the reduction of nucleic acid synthesis.

Clinically, chloroquine phosphate powder is mainly used to treat chloroquine-sensitive falciparum malaria, vivax malaria and three-day malaria. And can be used for inhibiting prevention of malaria symptoms. It can also be used for the treatment of extraintestinal amebiasis, connective tissue diseases, light-sensitive diseases (such as sun erythema), etc.

2. Combination medication Reasonable drug combination can enhance the curative effect or reduce adverse drug reactions, otherwise it can lead to decreased curative effect or increased toxicity, and some abnormal reactions may occur, which may interfere with treatment and aggravate the condition. In the treatment of malaria, chloroquine phosphate is usually used as a part of combination therapy, thus improving the therapeutic effect and reducing the occurrence of drug resistance. For example, when Chloroquine diphosphate powder is combined with other drugs (such as artesunate), it can effectively eliminate plasmodium in the body, thus shortening the course of disease, alleviating symptoms and reducing the risk of recurrence.

However, it should be noted that with the increasing adaptability of plasmodium to drugs, plasmodium in some areas has developed resistance to chloroquine phosphate tablets. Therefore, it is very important to make accurate diagnosis and drug sensitivity test before treatment to ensure the selection of the most effective treatment scheme.

3. Potential therapeutic effects on other diseases. In addition to malaria, chloroquine phosphate tablets have also shown potential curative effects on other diseases in the study. For example, in the treatment of some autoimmune diseases (such as rheumatoid arthritis and systemic lupus erythematosus), chloroquine diphosphate tablets are used as an immunomodulator, which is helpful to alleviate inflammation and improve symptoms. In addition, chloroquine phosphate tablets are also exploring the possibility as antiviral drugs, especially in the treatment research in novel coronavirus. We found that chloroquine phosphate, Favipiravir and a number of Chinese patent medicines have antiviral activity.

Our company can provide Chloroquine phosphate, Favipiravir and Artesunate at low prices. If you need it, please contact us by email:sales6@faithfulbio.com

What are the daily preventive measures and dietary recommendations for malaria?

For patients currently taking chloroquine phosphate tablets, in addition to following medical advice and taking medication on time, the following points should also be noted:
*Avoid drinking alcohol during treatment, as alcohol may interact with medication and affect treatment efficacy.
*Try to avoid consuming high-fat foods as they may increase liver burden, and chloroquine phosphate tablets are mainly metabolized by the liver.
*Maintaining sufficient water intake can help alleviate stomach discomfort that may be caused by medication.
*Regular blood tests should be conducted during and after treatment to monitor drug efficacy and potential side effects.
In summary, chloroquine phosphate tablets, as an important antiparasitic drug, play an irreplaceable role in the treatment of malaria. Meanwhile, with the deepening of research, its potential for application in other disease fields is gradually emerging. However, during use, patients need to strictly follow medical advice, pay attention to drug interactions and possible side effects, to ensure the safety and effectiveness of treatment.

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