N-Acetylcarnosine is a natural dipeptide containing histidine, which is the main source of L-carnosine in pharmacology.N Acetyl Carnosine Powder is a natural compound that is chemically classified as dipeptide Muscle alkaline to Related. The molecular structure of NAC is the same as that of muscle alkali, except that it carries an additional acetyl group. Acetylation makes NAC more resistant to degradation by sarcosinase, an enzyme that breaks down sarcosine into its constituent amino acids, alanine, and histidine.
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Item |
Standard |
Test Results |
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Appearance |
Off-white or white powder |
white powder |
|
HPLC Identication |
Consistent with the reference substance main peak retention time |
Conforms |
|
Specific Rotation |
+20.0° ~ +22.0° |
+20.9° |
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Heavy Metals |
≤10ppm |
Conforms |
|
PH |
7.5 ~ 8.5 |
8.2 |
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Loss on dry |
≤1.0% |
0.04% |
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Lead |
≤3ppm |
Conforms |
|
Arsenic |
≤1ppm |
Conforms |
|
Cadmium |
≤1ppm |
Conforms |
|
Mercury |
≤0.1ppm |
Conforms |
|
Melting Point |
250.0°C ~ 265.0°C |
253.6°C ~ 254.8°C |
|
Residue on Ignition |
≤0.1% |
0.04% |
|
Hydrazine |
≤2ppm |
Conforms |
|
Bulk density |
- |
0.24g/ml |
|
Tapped density |
- |
0.48g/ml |
|
L-Histidine |
≤0.3% |
0.05% |
|
Assay |
99.0% ~ 101.0% |
99.6% |
|
Total aerobes counts |
≤1000cfu/g |
30cfu/g |
|
Mold & Yeast |
≤100cfu/g |
40cfu/g |
|
E.Coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
| Conclusion: | Conform with enterprise specification . |
N-acetyl carnosine has More stronger antioxidant power than L-Carnosine!
L-carnosine is a low molecular weight water-soluble biopeptide composed of alanine and histidine, which exists in the left-handed form in mammalian tissues. As is well known, myopeptides are a powerful antioxidant component. However, in the comparative laboratory, the erythema of the creatine solution decreased by 3.6% (compared to the minimum erythema amount), and N-acetylcarnosine decreased by 7.3%. Because we can infer that the antioxidant capacity of creatine in a 0.5% aqueous solution is weaker than that of N-acetylcarnosine. And scientific research has once again confirmed that this gap lies in the fact that N-acetylcarnosine can significantly improve the carrier of substances through the skin barrier. The high-quality skin penetration performance makes n-acetyl carnosine an interesting hydrophilic antioxidant in dermatological preparations.
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| 56353-15-2 N-Acetylcarnosine | 305-84-0 L-Carnosine |
Our company can provide various N-Acetylcarnosine;L-Carnosine etc. If you are interested, please contact us via email:sales6@faithfulbio.com
What is the difference between acetylcarnosine and Botulinum toxin type a ?
N Acetyl Carnosine Powder and botulinum toxin are two substances related to nerve transmission and muscle movement, and there are significant differences in chemical structure, mechanism of action, application field and duration of action.
1. Chemical structure: Acetylcarnosine is a neurotransmitter, which is synthesized by acetylcholine synthase. Its molecular structure is relatively small, including acetyl and choline groups. Botulinum toxin is a neurotoxin, a protein toxin produced by Botulinum botulinum. The structure is complex, and it is composed of several protein subunits, with two parts: heavy chain and light chain, in which the light chain is neurotoxic.
2. Mechanism of action: Acetyl Carnosine binds to acetylcholine receptor at neuromuscular junction, transmits nerve impulse and triggers muscle contraction. Botulinum toxin blocks the transmission of nerve impulses by inhibiting the release of acetyl carnosine, which leads to muscle contraction.
3. Application field: Acetylcarnosine mainly exists in the nervous system and is an important molecule for transmitting nerve impulses. Botulinum toxin is widely used in medicine and can be used to treat muscle spasm, facial wrinkles, excessive sweating and other symptoms.
4. Duration of action: The duration of action of acetyl carnosine is short, and once released to the neuromuscular junction, its action will end relatively quickly. The effect of botulinum toxin lasts for a long time, and it can last for several months after one use.
matters needing attention:Patients should use the above drugs under guidance to avoid harm to their health.
Regarding the issue of N-acetylcarnosine and age-related cataracts.
We know that oxidation refers to the phenomenon that cells are damaged due to excessive reactive oxygen species. Although, the human body has the antioxidant effect of inhibiting reactive oxygen species. However, this function will gradually decline with the increase of age. This decline in generative function is also the direct cause of cataract.
In fact, cataract is also a white turbidity phenomenon caused by the damage of this oxidized lens. So 90% of cataracts are caused by aging.
Cataracts can be suppressed when the human body produces this carnosine. The antioxidant function of inhibiting this oxidation. It is a natural amino acid called carnosine. Studies have proved that N-acetyl carnosine can be used to supplement carnosine by decomposing carnosine without adding water.
Saccharification refers to the denaturation of substances such as protein and fat when they react with sugar. The phenomenon of glycosylation was first discovered in 1968. Researchers discovered the phenomenon that hemoglobin reacts with sugar in blood, and called this glycosylated hemoglobin "glycosylated hemoglobin". Glycosylation not only leads to diabetes, but also causes various chronic diseases such as hypertension, cataract, kidney disease, Alzheimer's disease and decreased immunity, which must be paid attention to.
Especially cataract, after data comparison, we will find that the content of glycosylated hemoglobin in cataract patients is very high. Scientists speculate that if the types of carnosine produced by chemical synthesis are endowed with the characteristics of transforming into the original carnosine in the body, (like N Acetyl Carnosine Powder) may be beneficial to the treatment of cataract.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Can provide you with a good price.Our company can provide various N-Acetylcarnosine;L-Carnosine etc. If you are interested, please contact us
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