Retigabine CAS 150812-12-7

Name: China Retigabine CAS 150812-12-7 Suppliers, Manufacturers, Factory - Wholesale Price - Faithful Biotech
Brand: Faithful
SKU: 301188554

Product Name:Retigabine
Synonym:RetigabineDiscontinued See: R189051;2-AMINO-4-(4-FLUORBENZYLAMINO)-1-ETHOXYCARBONYLAMINOBENZENE;D2312;D 23129;Retigabin;Ezogabine impurity
CAS NO.:150812-12-7
EINECS NO.:629-886-2
Molecular Formula:C16H18FN3O2
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months

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Description

Retigabine CAS 150812-12-7 is a central nervous system regulator with a novel mechanism of action and one of the world's first specific regulators targeting neuronal potassium channels. It has been widely used in adjunctive intervention research and clinical applications for neurological disorders related to abnormal excitation, providing a new research direction and practical pathway for the regulation of these neurological conditions.

The core characteristic of this substance is its ability to precisely act on the KCNQ family voltage-gated potassium channels in the human brain. It can effectively activate key channels such as KCNQ2 and KCNQ3, enhance the M-current effect in neurons, promote the maintenance of hyperpolarization of the neuronal cell membrane, stabilize the resting potential of neurons at its source, and inhibit abnormal and excessive high-frequency discharge of nerve cells, thereby calming the abnormally excited state of the brain. This approach differs from the action pathways of traditional neuroregulatory substances, possessing unique targeted regulatory advantages.

Tests	Specifications	Results
Appearance	White to off-white to pale yellowish crystalline powder	Complies
Identification(HPLC)	Retention time of sample matches reference standard	Complies
Assay	≥99.0%	99.6%
Related Substances	Any Individual Impurity≤0.1%	0.03%
Related Substances	Total Impurities≤1.0%	0.35%
Loss on Drying	≤0.5%	0.2%
Residue on lgnition	≤0.1%	0.04%
Heavy Metals	Lead(Pb)≤2.0 ppm	Complies
	Cadmium(Cd)≤1.0 ppm	Complies
	Mercury(Hg)≤1.5 ppm	Complies
	Total Heavy Metals≤10 ppm	Complies
Microbial Limits	Total Plate Count<1000cfu/g	<100cfu/g
	Yeast &Moulds<100cfu/g	<10cfuv/g
	E.Coli Negative	Negative
	Salmonella Negative	Negative
Conclusion	Conform with enterprise specification

Density 1.3±0.1 g/cm³
Boiling point 430.0±45.0 °C at 760 mmHg
Molecular formula C16H18FN3O2
Molecular weight 303.331
Flash point 213.9±28.7 °C
Exact mass 303.138306
PSA 76.38000
LogP 0.81

Target: Selectively activates voltage-gated potassium channels KCNQ2/3/4/5 in the brain

Effects: Stabilizes channel opening, enhances M-current
Induces neuronal membrane hyperpolarization, stabilizing resting potential
Inhibits abnormal neuronal overexcitation and synchronous firing

Additional Effects: Enhances GABAergic inhibition and reduces glutamate release.

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With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.

Retigabine CAS 150812-12-7

Transportation Time	Shipping method	Cargo weight requirements	Advantage
3-7 days	DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS	Suitable for under 50kg. International door to door express	We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.
7-15 days	By Air	Suitable for more than 50kg. fast and cheaper for large order
15-60 days	By Sea	Suitable for more than 500kg. Cheapest shipping way

Retigabine is a central nervous system regulator with a novel mechanism of action. It is also one of the world's first specific regulators targeting neuronal potassium channels. It has been widely used in adjunctive intervention research and clinical settings for conditions related to abnormal excitation of the nervous system, opening up new research and practical directions for the regulation of related neurological disorders.

This substance has significant safety limitations. Long-term exposure can trigger various physical reactions, including not only central nervous system-related problems such as dizziness, mental fatigue, confusion, and tremors, but also specific visual pigment deposition, abnormal color perception, and metabolic excretion disorders. Some of these adverse effects are irreversible, causing persistent negative effects on human senses and bodily functions.

You can contact the following email address: sales4@faithfulbio.com

Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.

Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.

Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

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