Mitotane Powder CAS 53-19-0
Product Name:Mitotane powder
CAS NO.:53-19-0
Molecular Formula:C14H10Cl4
EINECS.NO:200-166-6
Synonym:Mitotan;LYSODREN;2,4'-TDE;2,4'-DDD;
(2,4'-DICHLORODIPHENYL)DICHLOROETHANE
Test Method:HPLC/UV
MOQ & Package: 10g,100g,1kg etc Sub-package
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Description
Overview of Mitotane：
Mitotane is a kind of targeted drugs, which is mainly used for patients who can't be operated or have metastatic adrenal cortical carcinoma.
Mitotane powder appears as a white to beige powder, and its solubility in DMSO is 20mg/mL, which is clear.
| Product name | Mitotane |
| CAS | 53-19-0 |
| Molecular formula | C14H10Cl4 |
| Molecular weight | 320.04 |
| EINECS Number | 200-166-6 |
| Melting point | 77-78 °C(lit.) |
| boiling point | 405.59°C (rough estimate) |
| Appearance | White to off-white |
| Storage condition | Inert atmosphere,Room Temperature |
| Density | 1.3118 (rough estimate) |
product Specification
| Item | Specification | Results | |
| Assay | 98% | Complies | |
| Apperence | White Powder | Complies | |
| Particle Size | 100% pass 80 mesh | Complies | |
| Oder | Characteristic | Complies | |
| Taste | Characteristic | Complies | |
| Loss on Drying | ≤5.0% | 2.20% | |
| Residue on Ignition | ≤0.1% | 0.05% | |
| Residual | ≤0.1% | Complies | |
| Residual Ethanol | ≤0.5% | Complies | |
| Heave Mentals | ≤10ppm | Complies | |
| Na | ≤0.1% | <0.1% | |
| Pb | ≤3 ppm | Complies | |
| Total Plate | <1000CFU/g | Complies | |
| Yeast & Mold | <100 CFU /g | Complies | |
| E. Coli | Negative | Complies | |
| Salmonella | Negative | Complies | |
| Conclusion: The test results are conformed to the in-house specification | |||
What is the role and characteristics of mitotane?
The function and characteristics of mitotane, also known as acetone piperazine in mitotane, are also used to treat certain types of adrenocortical carcinoma. It can relieve symptoms by inhibiting hormone production in adrenal cortex and try to control tumor growth.
1. Mechanism of action
Mitotane plays a drug role in vivo mainly by inhibiting the function of adrenal cortical cells. It can destroy mitochondria in adrenocortical cells and hinder the synthesis and release of adrenocortical hormones.
Specifically, Mitotane powder interferes with the metabolism of cholesterol in mitochondria and inhibits the synthesis of enolase and proteasome, thus reducing the synthesis of adrenocortical hormone. In addition, it can also have a direct toxic effect on adrenal cortical cells and reduce the cell proliferation of adrenal cortical tumors.
2. Characteristics of mitotane
2.1 Treatment for adrenocortical carcinoma.Mitotane is widely used to treat adrenocortical carcinoma. The medicine can inhibit and destroy cancer cells, reduce the volume of tumor, reduce the risk of distant metastasis and prolong the survival time of patients.
2.2 Control adrenal cortical hyperplasia and hypercortisolism Mitotane powder controls the occurrence of cortical hyperplasia and hypercortisolism by inhibiting the synthesis of cortisol. It can reduce the level of cortisol, improve related symptoms, such as hypertension and glucose metabolism disorder, and reduce the risk of complications related to enolase deficiency.
How and where to buy Mitotane powder wholesale?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details, Click email：sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales7@faithfulbio.com Now.
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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