API Vinorelbine Tartrate Powder CAS 125317-39-7

API Vinorelbine Tartrate powder is a derivative of vincristine and its action is similar to vincristine. It was first listed in France in 1989. Its main function is to bind to tubulin, which hinders the formation of microtubules during mitosis. Changchun Rui bin is a cyclical-specific drug. It is commonly used in the treatment of non-small cell lung cancer (NSCLC) and breast cancer, ovarian cancer, head and neck cancer, and leukemia, and also has a strong inhibitory effect on small cell lung cancer, and colon cancer, brain tumor, and malignant melanoma.

What are the side effects of vinorelbine tartrate soft?

The toxic and side effects of API Vinorelbine Tartrate powder are closely related to the dosage. The side effects of this product are bone marrow suppression, manifested in granulocytopenia, anemia, and occasional thrombocytopenia.

Other common adverse reactions were nausea, vomiting, and hair loss. sometimes phlebitis can occur.

Neurotoxicity is lighter than vincristine. Peripheral neurotoxicity is generally limited to the disappearance of deep tendon reflex, and sensory abnormalities are rare. Lower limb weakness can occur after long-term treatment. The main manifestation of autonomic neurotoxicity is constipation caused by small intestinal paralysis, and paralytic intestinal obstruction is rare. Occasional adverse reactions include arrhythmia, dyspnea, bronchospasm, impaired liver function, and so on.

How to deal with the above adverse reactions?

To deal with the adverse reactions to this API Vinorelbine Tartrate powder, the first thing is to strictly control the dosage, especially when the individual is intolerable, the doctor should be informed in time for dose adjustment, and the use of this drug should be suspended in severe cases.

In addition, mild side effects can be treated according to symptoms. For example, anemia needs to eat more blood tonic food, and severe anemia needs a blood transfusion.

In order to prevent serious adverse reactions, rare ginsenosides can be used before chemotherapy with vinorelbine, and they can be used for a long time, which can reduce toxicity and increase efficiency.

Rare ginsenosides are components with anticancer activity extracted from ginseng, American ginseng, Panax-Notoginseng, etc. Researchers found that rare ginsenosides can not only directly inhibit the growth and proliferation of cancer cells and promote cancer cell apoptosis, but also alleviate and reduce the toxic and side effects of anticancer drugs, reducing toxicity and increasing efficiency.

Does vinorelbine tartrate have a good anti-cancer effect?

Lung cancer has no special symptoms in the early stage. It is only the common symptoms of general respiratory diseases, such as cough, phlegm and blood, low fever, chest pain, stuffy breath, and so on. Chest pain in the early stage of lung cancer is mild, mainly manifested as muggy pain, dull pain, uncertain location, and an uncertain relationship with respiration. If flatulence and pain continue to occur, it indicates that cancer may involve the pleura. Because lung cancer is prone to distant metastasis in the early stage, the symptoms related to distant metastasis are often the first symptoms found by doctors or patients.

vinorelbine tartrate powder is a semi-synthetic Catharanthus roseus alkaloid. It mainly binds to tubulin to hinder the formation of microtubules in the process of mitosis; At high concentration, it can block the cells from the G2 phase to the M phase. Patients should take medicine under the guidance of doctors. To prevent and treat lung cancer, we must quit smoking and alcohol, and develop good living habits.

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