The appearance of Erlotinib hydrochloride powder is white, off white, or yellow. Clinically, it is mainly used for second or third line treatment of locally advanced or metastatic non-small cell lung cancer and pancreatic cancer. It is a small molecule epidermal growth factor receptor tyrosine kinase reversible inhibitor. Research has found that pure ERLOTINIB HCL SALT has inhibitory effects on various tumors, and compared with traditional chemotherapy drugs, it has advantages such as less adverse reactions, better safety and tolerability.
| structural formula |
|
|
|
Item |
Standard |
Test Results |
|
Appearance |
White or light yellow powder |
Complies |
|
Identification |
The principal peak in the chromatogram obtained with the test solution is similar in retention time to principal peak in the chromatogram obtained with the reference solution. |
Complies |
|
Impurities |
Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
|
Mineral count |
≤4.0 % |
1.53% |
|
Residue on ignition |
≤3% |
0.05% |
|
Chromatographic purity |
Should Conform |
Complies |
|
Loss on drying |
≤ 3% |
0.3% |
|
Moisture |
≤ 0.3% |
0.15% |
|
Coliforms (MPN/100g) |
≤10 |
Negative |
|
Mold |
≤50 CFU/g |
Negative |
|
Salmonella |
Negative |
Complies |
|
Staphylococcus aureus |
Negative |
Complies |
|
purity |
≥98% |
98.9% |
| Conclusion： |
Conforms to USP32 . |
|
What generation of targeted drugs is Erlotinib hydrochloride?
Erlotinib hydrochloride powder is a first generation targeted drug mainly used to treat non-small cell lung cancer patients carrying EGFR mutations. The details of this product are as follows:
1. Mechanism of action of ERLOTINIB HCL: Erlotinib hydrochloride is an inhibitor of epidermal growth factor receptor (EGFR), which inhibits the signal transduction of EGFR, thereby suppressing the growth and spread of tumor cells. In non-small cell lung cancer patients carrying EGFR mutations, it has good efficacy and low toxicity.
2. The difference between ERLOTINIB HCL SALT and other targeted drugs: The first generation of targeted drugs such as gefitinib and erlotinib mainly target EGFR sensitive mutations, while the second generation of targeted drugs such as Afatinib (BIBW 2992) and Dacomitinib (PF299804) can target sensitive and partially resistant mutations. Compared to the previous two generations of targeted drugs, the third generation of targeted drugs have more significant advantages in terms of therapeutic efficacy, tolerance, and drug resistance.
3. Scope of application and precautions of Erlotinib hydrochloride: Erlotinib is mainly suitable for patients with advanced non-small cell lung cancer carrying EGFR mutations. Before using it for treatment, patients need to undergo genetic testing to determine if they carry the corresponding mutation. During the treatment process, patients should undergo regular check ups as recommended by their doctors to evaluate efficacy and monitor potential toxic side effects.
98% purity Erlotinib hydrochloride is a first generation targeted drug with good efficacy and low toxicity, mainly used to treat non-small cell lung cancer patients carrying EGFR mutations. Before using it for treatment, patients need to undergo genetic testing to determine if they carry the corresponding mutation, while following the doctor's advice and monitoring during the treatment process.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Erlotinib hydrochloride powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.
If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com . Our team is committed to ensuring the complete satisfaction of customers.
Hot Tags: erlotinib hydrochloride cas 183319-69-9, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China