Bosutinib Powder CAS 380843-75-4
Product Name:Bosutinib powder
CAS NO.: 380843-75-4
Molecular Formula:C26H29Cl2N5O3
EINECS.NO:700-455-1
Synonym:Bosutinib ( SKI-606 );Bsutinib;
SKI 606 - Bosutinib;CS-311;Bosutinib for research;Bosutinib(TINIBS )
Test Method:HPLC/UV
MOQ & Package: 10g,100g,1kg etc Sub-package
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Description
Overview of Bosutinib：
Bosutinib is a potent protein kinase inhibitor, which can inhibit both the spontaneous phosphorylation of Src protein and the phosphorylation of Src and Ab1 substrates in various human tumor cells.
Bosutinib powder is grayish white to light brown , and its solubility in DMSO is ≥15mg/mL, and it remains stable for 2 years from the date of purchase. DMSO solution can be stored at-20 C for up to one month.
| Product name | Bosutinib |
| CAS | 380843-75-4 |
| Molecular formula | C26H29Cl2N5O3 |
| Molecular weight | 530.45 |
| EINECS Number | 700-455-1 |
| Melting point | 116-120 ºC |
| boiling point | 649.7±55.0 °C(Predicted) |
| Solubility | Solubility in DMSO ≥15mg/mL. |
| Appearance | Grayish white to light brown powder |
| Storage condition | room temp |
| Density | 1.36 |
How does bosutinib exert its therapeutic effect?
Compared with other leukemia drugs, bosutinib powder has higher selectivity and efficacy. It mainly acts on specific tyrosine kinases in bone marrow cells, but has little effect on normal cells. This feature makes it not bring too many adverse side effects to patients during treatment.
Bosutinib plays a therapeutic role mainly by inhibiting tyrosine kinase in cancer cells.
Bosutinib powder, as a tyrosine kinase inhibitor, plays a therapeutic role mainly by inhibiting tyrosine kinase in cancer cells. This drug can interfere with the signal transduction pathway in cancer cells, block the growth and division of cancer cells, and then inhibit leukemia.
Bosutinib can also be used to treat other hematological malignancies.
Besides treating CML, bosutinib can also be used to treat other hematological malignancies. For example, Bosutinib powder has also shown certain efficacy in the treatment of some frontline myeloid leukemia. In addition, the study also shows that CS-311 may have certain anti-tumor effect on other types of leukemia and solid tumors.
product Specification
| Item | Specification | Results | |
|
Appearance |
Grayish white to light brown powder | Complies | |
| Assay | ≥99% | 99.35% | |
|
Odor |
Complies | Characteristic | |
| Mesh Size | 80 mesh | Complies | |
| Loss On Drying | ≤0.5% | 0.27% | |
| Residue On Ignition | ≤1.0% | 0.45% | |
| Heavy Metals | <5ppmMax | Complies | |
| As | <2ppm | 0.3ppm | |
| Total Plate Count | < 1000/g Max | Complies | |
| Yeast & Mold | <100/g Max | 31/g | |
| Conclusion: The test results are conformed to the in-house specification | |||
Which generation of targeted drugs is bosutinib ?
How and where to buy bosutinib powder wholesale?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
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A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales7@faithfulbio.com Now.
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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