Salinomycin CAS 53003-10-4
Product Name:Salinomycin
CAS NO.:53003-10-4
Molecular Formula:C42H70O11
EINECS.NO:258-290-1
Synonym:Salinomycin;SALINOMYCIN SODIUM;Antibiotic-61477;Procoxacin
Lead Time:1-3 days
Shipping:DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life:Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany
Description
what is Salinomycin?
Salinomycin is a polyether antibiotic extracted from the culture medium of Streptomyces albopictus, belonging to the ion carrier type antibiotic. It generally exists in the form of sodium salt of salinomycin, which is a white or light yellow crystalline powder with a slight specific odor, stable properties, and insoluble in water.
 |
Product name |
Salinomycin |
|
CAS |
53003-10-4 |
|
|
Molecular formula |
C42H70O11 | |
|
Molecular weight |
751 | |
| EINECS | 258-290-1 | |
|
Appearance |
white powder |
|
|
Melting point |
112.5-113.5°C(lit.) | |
| Storage | Sealed in dry,2-8°C | |
| Density |
1.18±0.1g/cm3(Predicted) |
What are the use of Salinomycin?
|
|
Salinomycin is a highly effective, broad-spectrum, low resistance, and low residue antibiotic, which is a broad-spectrum anti coccidioid drug. It has significant bactericidal and bacteriostatic effects on Gram positive bacteria, fungi, pathogenic insects, coccidia, etc. Salinomycin has significant effects on various types of Eimeria such as chicken heap type, Brucella, giant, displaced, toxic, and tender. Its anti coccidial activity is roughly similar to Monensin and Halofuginone. If you need it, pls click e-mail sales1@faithfulbio.com |
what is the mechanism of Salinomycin?
|
|
The mechanism of action of Salinomycin is that it can bind with sodium and potassium ions to form complexes in developing insects, affecting the transport of potassium ions into the mitochondria of nematodes, and inhibiting certain mitochondrial functions of nematodes, including substrate oxidation and ATP hydrolysis. |
Product Specification
|
Items |
Specifications |
Results |
|
Appearance |
Brown yellow granules |
Conform |
|
Identification |
Ethanol solution of the substance to be examined reacting with vanillin test solution shows red. |
Positive reaction |
|
Particle size |
Not less than 95% pass through a 24 mesh sieve. |
100% |
|
Loss on drying |
≤8.0% |
0.9% |
|
Heavy metals |
≤0.0020% |
＜0.0020% |
|
Arsenic |
≤0.0002% |
＜0.0002% |
|
Salinomycin A |
≥85.0% |
94.2% |
|
Related substances |
Any single impurity≤5.0% |
Conform |
|
Total impurities≤10.0% |
5.8% |
|
|
Assay |
Potency for report only |
120U/MG |
|
90.0～110.0% |
100.0% |
Conclusion：Conform with specification and qualified.
How to Biosynthesis Salinomycin?
A research team has cloned and sequenced the biosynthetic cluster responsible for salinomycin production, from Streptomyces albus DSM 41398.This has shown that the polyketide backbone of salinomycin is synthesised on an assembly line of nine polyketide synthase) multienzymes. Furthermore, the cluster contains genes involved in oxidative cyclization including salC (epoxidase) and salBI/BII/BIII (epoxide hydrolase) genes. The cluster also contains genes suspected to be involved in self-resistance, export, precursor supply and regulation. The cluster contains a NRPS[clarification needed]-like carrier protein, SalX, that is suspected to tether "pre-salinomycin" during oxidative cyclization. By inactivating salC the researchers have demonstrated that salinomycin biosynthesis proceeds via a diene intermediate.
How and where to buy Salinomycin?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Disclaimer: The articles on this website are mainly used for scientific research and academic exchange. Please carefully discern the authenticity of their viewpoints and content. If you discover any infringement. Please contact the administrator promptly. We are not responsible for the consequences of the information and services provided on this website.
Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
Send your Inquiry for more details, Click email：sales1@faithfulbio.com Now.
Hot Tags: salinomycin cas 53003-10-4, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China
Send Inquiry
You Might Also Like
