Sulfadiazine Powder CAS 68-35-9

Sulfadiazine powder is White or off white crystalline, easily soluble in dilute hydrochloric acid, sodium hydroxide solution, or ammonia solution. If long-term exposure to light gradually darkens. Sulfadiazine sodium salt is white crystalline powder, If long-term exposure to light gradually turns brown, it will slowly absorb carbon dioxide and precipitate Sulfadiazine in humid air.This product is easily soluble in water, with a pH value of 9.5-10.5 for a 10% aqueous solution.It is a commonly used sulfonamide anti infective material in clinical practice in China

What are the pharmacological effects of Sulfadiazine Powder?

Sulfadiazine Powder is structurally similar to p-aminobenzoic acid (PABA) and can compete with PABA to act on dihydrofolate synthase in bacteria, thereby preventing PABA from being used as a raw material to synthesize folate required by bacteria and reducing the amount of metabolically active tetrahydrofolate, which is an essential substance for bacterial synthesis of purine, thymidine, and deoxyribonucleic acid (DNA), thus inhibiting bacterial growth and reproduction. Sulfadiazine is the product with the lowest plasma protein binding rate and the highest blood-cerebrospinal fluid barrier permeability among sulfonamides, and has outstanding efficacy in preventing and treating epidemic meningitis; However, due to the low solubility of 98% pure Sulfadiazine Powder in urine, crystallization urine is prone to occur, making it unsuitable for the treatment of urinary tract infections.

The function and efficacy of Sulfadiazine zinc salt?

Sulfadiazine Powder is a class of antibiotics widely used in the veterinary and pharmaceutical fields for the treatment of infection cases. However, in clinical practice, this product has also shown effectiveness in the immune system and pain relief

1. Antibacterial and anti infective properties
Sulfonamide pyrimidine is an antibacterial drug that can effectively inhibit the growth and reproduction of various bacteria. It is mainly used to treat various bacterial infections caused by sensitive strains, such as urinary tract infections, intestinal infections, lung infections, meningitis, and cerebrospinal meningitis.

2. Immune regulation
The sulfonamide components in sulfamethoxazole have immunomodulatory effects and can affect the body's immune response process, making them suitable for the treatment of autoimmune diseases.

3. Relieve fever and relieve pain
Sulfonamide can inhibit the hypothalamic thermoregulatory center, reduce the synthesis of prostaglandin E2, and thus lower the body temperature of fever patients. At the same time, it also has the effect of inhibiting nerve conduction and can be used to alleviate mild to moderate pain, such as headaches, joint pain, etc.

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