What is Moxidectin ?
Moxidectin is a semi-synthetic single-component macrolide antibiotic produced by Streptomyces fermentation, and it is a derivative of nimodipine. Macrolide antiparasitic drugs are composed of two categories, namely avermectins and milbemycin. Moxidectin powder appears as a white to nearly white solid.
| Product name |
Moxidectin powder |
| CAS | 113507-06-5 |
| Molecular formula | C37 H53 N O8 |
| Molecular weight | 639.82 |
| EINECS Number | 635-129-7 |
| melting point | 132 °C |
| boiling point | 790.0±70.0 °C(Predicted) |
| density | 1.23±0.1 g/cm3(Predicted) |
| solubility | Under mild heating and ultrasonic wave, the water is ≥3.27 mg/mL. |
| Storage condition | Inert atmosphere,Room Temperature |
What are the pharmacological effects and indications of Moxidectin?
Moxidectin powder is a broad-spectrum antiparasitic drug, which has high repellent activity against nematodes and arthropod parasites in cattle, horses, sheep, dogs and other animals. Compared with other multi-component macrolide antiparasitic drugs, it is different from other multi-component macrolide antiparasitic drugs in that it has a single component and can maintain the anti-insect activity for a longer time (it has higher fat solubility, so it can maintain the therapeutically effective drug concentration of tissues for a longer time).
Moxidectin powder is used as a new generation of veterinary anthelmintics (It is a macrolide anthelmintic antibiotic, which came out as early as 1960s, so moxifloxacin is a typical new batch of old drugs), which can effectively kill nematodes and surface parasites, and has good safety for animals. It is superior to ivermectin in dosage, formulation development, drug resistance and drug distribution in vivo. Mainly targeted at nematodes and arthropod parasites of cattle, horses, sheep, dogs and other animals.
Product Specification
| Item | Specifications | Result |
| Appearance | White to off-white powder | complies |
| Assay(on dried basis) | ≥98.0% | 99.2% |
| Loss on drying | ≤5.0% | 0.26% |
| Total number of colony | ≤1000cfu/g | 50 cfu/g |
| Saccharomycetes /mould | ≤50 cfu/g | 10 cfu/g |
| Heavy metals(as Pb) | ≤0.001% | complies |
| As | ≤3ppm | complies |
| Water insoluble | ≤0.01% | complies |
| Conclusion: The test results are conformed to the in-house specification | ||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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