What is Carbasalate calcium ?
Carbasalate calcium is an aspirin derivative, which is a salt formed by complexing calcium acetylsalicylate with urea. The metabolic characteristics and pharmacological effects of Carbasalate calcium are the same as those of aspirin. In water, calcium carbapirine is hydrolyzed to acetylsalicylic acid, which effectively plays the roles of antipyretic, analgesic, anti-inflammatory and aggregation inhibition.
| Product name |
Carbasalate calcium |
| CAS | 5749-67-7 |
| Molecular formula | C10H14CaN2O5 |
| Molecular weight | 282.31 |
| EINECS Number | 227-273-0 |
| form | powder |
| colour | White to white-like |
| solubility | Soluble in water and dimethylformamide. |
| Storage condition | Inert atmosphere,Room Temperature |
What is the pharmacological action of Carbasalate calcium ?
Carbasalate calcium is a white crystalline powder, slightly bitter in taste and easily soluble in water. It is a complex of calcium acetylsalicylate and urea, and has the same metabolic characteristics and pharmacological effects as aspirin. It has antipyretic, analgesic, anti-inflammatory and platelet aggregation inhibiting effects, and prevents thrombosis caused by various reasons. It will be absorbed quickly, take effect quickly, and has high bioavailability. It will be metabolized by the liver and excreted by the kidney. Carbasalate calcium has stronger antipyretic and analgesic effects, less adverse reactions and almost no irritation to gastrointestinal mucosa.
What are the indications of Carbasalate calcium?
Carbasalate calcium can treat fever and inflammation of poultry and livestock. It can be used as an auxiliary drug in the treatment of avian influenza, nephroma and other poultry diseases. Carbasalate calcium is clinically used for common cold, fever, headache, toothache, neuralgia, muscle, rheumatism and rheumatoid arthritis, and for preventing transient ischemic attack, myocardial infarction or postoperative thrombosis.
Product Specification
| Item | Specifications | Result |
| Appearance | White to off-white powder | complies |
| Assay(on dried basis) | ≥98.0% | 99.56% |
| Identification | Infrared spectrum should be the same as the spectrum for reference spectrum | Complies |
| It gives the reaction of Calcium | Complies | |
| Absorption maxima at 228nm and 276nm» specify absorbance should be 363 to 379 at 228nm and 49 to 53 at 276nm. | Complies | |
| The solution gives reaction of salicylates | Complies | |
| Heat sample with sodium hydioxide, a colour yellow or yellowwish-brown is produced and the vapour turns red litmus paper blue. | Complies | |
| Related substances | Impurity C should not more than 0.5% | 0.37% |
| Impurity B should not more than 0.15% | 0.02% | |
| Any unspecified impurities should not more than 0.05% | 0.02% | |
| Total impurities should not more than 0.7% | 0.40% | |
| Heavy Metals | Not more than lOppm | Complies |
| Water | Should not more than 0.1% | 0.04% |
| Conclusion: The test results are conformed to the in-house specification | ||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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