Product description
Albendazole is one of the broadest deworming agents of benzimidazole with the strongest insecticidal action. It is mainly used for the treatment of single or mixed infections caused by roundworm, pinworm, whipworm, hookworm Americanus, hookworm duodenum, and steroidium, as well as mixed infections caused by tapeworm and these intestinal worms. Albendazole sulfoxide is the main metabolite of Albendazole, and the insecticidal activity of ABZ is mainly derived from ASON.
The two enantiomers of the same compound not only have different optical properties and physicochemical properties, but also have different biological activities, such as pharmacologically, inhibition of enzyme, binding to receptor and transfer of membrane are related to the stereochemistry of it. ASOX is a racemic enantiomer composed of D-ASOX and L-ASOX. The proportion of D-ASOX and L-ASOX in the host varies according to the host species, and whether there are significant differences in pharmacology, side effects and efficacy is not fully understood.
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COA
| ltems | Standard | Results |
| Appearance | White or almost white powder | Conform |
| Heavy Metals | ≦20ppm | Conform |
| Loss On Drying | ≦0.50% | 0.15% |
| Sulphated Ash | ≦0.30% | 0.08% |
| Residue on Ignition | ≦0.10% | 0.03% |
| Total Impurities | ≦1.0% | 0.03% |
| Residual Solvents | <3000ppm | Conform |
| Total Aerobic Count | ≦1000cfu/g | <1000cfu/g |
| Molds & Yeasts | ≦100cfu/g | <100cfu/g |
| Escherichis Coil | Not detective | undetected |
| Salmonellosis | Not detective | undetected |
| Assay | 99.0%-101.0% | 99.90% |
| Conclusion | Conform with enterprise specification | |
Density 1.4± 0.1g /cm3
Boiling point 357.3ºC at 760 mmHg
Melting point 154-156ºC
Molecular formula C12H15N3O3S
Molecular weight 281.331
Flash point 169.9ºC
Accurate mass 281.083405
PSA 103.29000
LogP 0.91
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What is the use of albendazole sulfoxide?
The active metabolite of albendazole – Albendazole sulfoxide – binds to, and inhibits, the polymerization of beta-tubulin. This inhibits cytoplasmic microtubule formation and glucose uptake within the parasite. This leads to immobilization and death of adult worms and prevents hatching of eggs.
Why is Albendazole Sulfoxide better than Albendazole?
Albendazole enters the human body and produces its main active metabolite, Albendazole Sulfoxide, through the action of liver microenzyme, which is further metabolized into Albendazole Sulfoxide. The insecticidal activity of ABZ was mainly derived from ABZSO, while ABZSO2 had no insecticidal activity. Therefore, the insecticidal activity of Albendazole Sulfoxide is superior to that of Albendazole.
What is Albendazole sulfoxide?
Albendazole Sulfoxide is a blood-brain barrier main metabolite of anti-parasitic agent albendazole that acts as a antihelminthic. It binds to colchicine binding site of beta -tubulin and prevents polymerization. Albendazole sulfoxide exhibits greater affinity to parasitic beta-tubulin than to mammalian.
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why choose us
Our Factory
Package
Shipping Methods
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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