Megestrol Acetate Powder CAS 595-33-5

Product Introduction

Megestrol acetate powder is a common intermediate. It can be obtained by ring-opening 16,17α-epoxyprogesterone with hydrogen bromide and debromination with nickel catalysis to generate 17α-hydroxyprogesterone, which is then acetylated and hydrolyzed with acid to generate 17α-acetoxyprogesterone, which is then etherified with triethyl orthoformate and subjected to Vilsmeier reaction to obtain 3-ethoxy-6-formyl-17α-acetoxypregn-2,5-diene-20-one, and finally reduced with potassium borohydride, hydrolyzed with acid, dehydrated and transposed to obtain the product.

Megestrol acetate powder Picture	Megestrol acetate powder MF

Product Application

Megestrol acetate powder gradually reduces resting plasma cortisol concentrations and cortisol concentrations. Megestrol acetate powder treatment for 9 days significantly increased food and water intake compared to untreated controls. Megestrol acetate significantly increased neuropeptide Y concentrations in the rat arcuate nucleus (where neuropeptide Y is synthesized), lateral thalamus (neurons passing through the arcuate), medial preoptic area, ventromedial nucleus, and dorsomedial nucleus .

 

 

product key technologies

01.

The synthesis process of Megestrol acetate powder is as follows: 16,17α-epoxyprogesterone can be used to generate 17α-hydroxyprogesterone through hydrogen bromide ring opening and nickel-catalyzed reduction debromination

02.

and then acetylated and acid hydrolyzed to generate 17α-acetoxyprogesterone, and then etherified with triethyl orthoformate and Vilsmeier reaction to obtain 3-ethoxy-6-formyl-17α-acetoxypregnatha-2,5-diene-20-one, and finally reduced with potassium borohydride, acid hydrolyzed, dehydrated and transposed to obtain the product.

Product Specification

How To Obtain Samples of Megestrol acetate powder?

Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Megestrol acetate powder.

The Best Megestrol acetate powder Manufacturer And Supplier

Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.

We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.

Why Choose Faithfulbio Megestrol acetate powder?

Faithfulbio specialize in Megestrol acetate powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.

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kindly note: Use Megestrol acetate powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.

Where To Buy Megestrol acetate powder?

Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!

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