Estriol Powder CAS 50-27-1

Estriol Introduction

Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.

As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.

Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.

Estriol Powder is a metabolite of estradiol and estrone. It is a white solid with the CAS number 50-27-1 and the molecular formula C18H24O3. Molecular weight: 288.38; EINECS number: 200-022-2Its value is very low in nonpregnancy and is mainly synthesized by the liver; During pregnancy, it is mainly synthesized by the fetal placenta. After synthesis, it is metabolized in the liver through maternal blood circulation and combined with sulfuric acid or glucuronic acid to form binding E3, which is discharged from urine. E3 plays an important role in regulating fetal intrauterine development and can affect the sensitivity of the pregnant uterus to oxytocin.

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What's The Difference Between Estriol And Estradiol?

Estriol Powder and β-Estradiol are the two main sex hormones produced by women. β-Estradiol is a pregnancy hormone that exists in large quantities only during pregnancy, while E3 is present in all women's bodies. The fetus and placenta naturally produce the E3 hormone. When a woman wants to know if she is pregnant, home pregnancy test strips will detect the corresponding E3 content to determine if the fetus is developing. E3 exists in the blood and is excreted through urine, so a simple urine test or blood test is sufficient to determine if a woman is pregnant. During pregnancy, doctors sometimes check the levels of β-Estradiol in women to confirm if the pregnancy is progressing normally. If a woman needs hormone replacement therapy, E3 and β-Estradiol can be synthesized. The E3 level reaches its peak between the ages of 12 and 40. During pregnancy, the estrogen level rises rapidly, and it gradually decreases after menopause. If a woman experiences menopausal symptoms or discomfort, some hormone supplements can be taken. β-Estradiol is also a sex hormone for pre-menopausal women and is crucial for sexual health and reproductive health, but it may also affect other body organs, such as the skeletal system. It is very similar to E3, but there are some differences. The content of β-Estradiol is higher in young women who are still fertile; while Estriol mainly comes from the fetus during pregnancy. Therefore, the Estriol levels of post-menopausal women and young women who are not pregnant are similar.

What is the function of estriol?

The E 3 related preparations include vaginal creams, suppositories, tablets, etc. They rely on local supplementation of mild estrogen to alleviate vaginal atrophy discomfort caused by the decline of estrogen levels after menopause. They can relieve vaginal dryness, burning, itching, and pain during sexual intercourse, enhance the body's own defense ability of the vaginal mucosa, and reduce the probability of repeated infections in the urinary and reproductive tracts.
The ingredients directly act on the vaginal mucosa, promote the growth of epithelial cells, increase the secretion volume of secretions, rebuild the weakly acidic environment of the vagina, and repair the healthy ecological balance of the vagina. Compared with systemic estrogen regulation methods, Estriol Powder has mild activity and a very low amount entering the body circulation. Under the conventional recommended dosage, it has little impact on the endometrium and breast. In most cases, it does not require the use of progesterone in combination; multiple studies have proved that proper use will not increase the risk of endometrial cancer and breast cancer.
This category belongs to prescription preparations and cannot be used at will. It requires professional assessment by a doctor to rule out conditions such as unexplained vaginal bleeding, estrogen-related tumors, etc. Follow the principle of the minimum effective dose, usually using 2 to 3 times a week. Based on one's own condition, it should be long-term adjusted as needed. It is prohibited to purchase privately or use blindly.

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Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Estriol powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

FAQ:

Q1:Who should not use Estriol?
Strictly prohibited: Pregnancy or breastfeeding, unexplained vaginal bleeding, having or suspected of having estrogen-related cancers, having active thrombotic diseases or severe liver diseases, etc.
Q2:Is it safe to use Estriol? Is there any risk involved with long-term use?
The estriol vaginal preparation is a topical medication. The amount absorbed into the bloodstream is extremely low, so the risk is much lower than that of systemic hormone therapies such as oral administration.
Q3:What should be noted during the use of estriol?

Regular physical examinations and paying attention to abnormal signs: If there is new vaginal bleeding, spotting or severe discomfort, stop taking the medicine immediately and consult a doctor.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

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