Product description
Estriol Micronized Powder is a natural hormone and a metabolic product of Estradiol in the body, mainly existing in urine. Estrogen activity is relatively low, approximately six times that of Estrone but weaker than Estradiol. It has no carcinogenic effect, and the level of Estradiol in the body does not change after use. Estriol has a selective effect on the vagina and cervical canal, but has no effect on the uterine body and endometrium. Animal experiments have shown that Estriol has a stronger effect on vaginal epithelial keratinization than Estradiol, promoting vaginal epithelial hyperplasia, keratinization of surface cells, mucosal angiogenesis and healing of vaginal epithelial injury. However, its effect on uterine weight gain in mice is relatively weak. At the same time, Estriol can enhance the function of cervical cells, promote the proliferation of cervical muscle fibers, and increase the elasticity and softness of the cervix.
In addition, Estriol has a feedback inhibitory effect on the hypothalamus and pituitary gland, but it does not inhibit ovulation. It only has a significant impact on the corpus luteum. Therefore, it can be used as an adjuvant drug for mid-term induced abortion and induced abortion, as well as for the treatment of various menstrual disorders. Estriol Micronized Powder also has a significant effect on the hematopoietic system, reducing the permeability and fragility of blood vessels, and can be used in the treatment of various types of bleeding. It also has the effect of rapidly increasing peripheral white blood cells. Generally, it takes effect 1 to 3 days after use, but the duration of action is relatively short. It is effective for the reduction of white blood cells caused by radiotherapy and chemotherapy.
COA
| ltems | Standard | Results |
| Appearance | White to practically white, odorless, crystalline powder. | white crystalline powder, odorless |
| Identification | A:IR B:UV | Conforms |
| Melting point | About280ºC | 281.5ºC |
| Solubility | Insoluble in water; sparingly soluble in alcohol; soluble , n ether, and in vegetable oils | Conforms |
| Completeness of solution | The solution is clear and free from undissolved solid. | Conforms |
| Loss on drying | ≤0.5% | 0.26% |
| Specific optical rotation | +54°~ +62° | +57.07° |
| Total impurities | ≤2.0% | Conforms |
| Residue on ignition | ≤0.1% | 0.06% |
| Assay | ≥98% | 98.63% |
| Conclusion | Conform with enterprise specification | |
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Density: 1.3±0.1 g/cm ³
Boiling point: 469.0±45.0 °C at 760 mmHg
Melting point: 280-282 °C(lit.
Molecular formula: C18H24O3
Molecular weight: 288.381
Flash point: 220.8±23.3 °C
Precise mass: 288.172546
PSA 60.69000
LogP 2.94
Molecular structure
1. Molar refractive index: 81.09
2. Molar volume (cm ³ /mol) : 229.6
3. Isotonic specific volume (90.2K) : 622.1
4. Surface tension (dyne/cm) : 53.8
5. Polarizability (10-24cm ³) : 32.14
What is Estriol Micronized Powder used for?
estriol micronized powder is a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching. A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen.
Is Estriol Micronized Powder a steroid?
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable.
Is Estriol Micronized Powder good for skin?
Like natural estrogen, estriol creams, and gels help decrease inflammation, too, helping skin and vaginal tissue maintain health over time.
Clinical significance of Estriol Micronized Powder
(1) When serum Estriol levels decline accompanied by elevated estradiol levels: It indicates poor placental function and often foretells premature birth. The level of Estriol in serum usually increases continuously as pregnancy progresses and only slightly decreases before delivery.
(2) Continuous monitoring of Estriol in pregnant women's serum can be used for the monitoring of high-risk pregnancies: If the Estriol content continues to decline, it indicates severe placental dysfunction, often resulting in intrauterine fetal growth retardation, preeclampsia, congenital malformations of the fetus, hydatidiform mole, and intrauterine stillbirth, etc.
(3) Monitoring of pregnant patients with diabetes: Monitoring Estriol at this time is helpful for understanding placental function and fetal development. The incidence of macrosomia in pregnant women with diabetes is about ten times higher than that in non-diabetic patients. During pregnancy with diabetes, the placenta secretes more Estriol, leading to an increase in serum Estriol levels. Therefore, the incidence of stillbirth in diabetic pregnant women is much higher than that in non-diabetic pregnant women. Thus, monitoring changes in blood and urine Estriol levels is helpful in determining the delivery period of diabetic pregnant women.
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Our Factory
Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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