What is Hydroxyprogesterone ?
17α- hydroxyprogesterone, sometimes referred to simply as hydroxyprogesterone, is an endogenous progesterone steroid hormone similar to progesterone, and it is also the precursor of many endogenous steroid hormones biosynthesis, including androgen, estrogen, glucocorticoid, mineralocorticoid and some neurosteroids. Hydroxyprogesterone powder is an endogenous progesterone and a chemical intermediate in the biosynthesis of other steroid hormones. It appears as a white to almost white powder.
| Product name |
Hydroxyprogesterone powder |
| CAS | 68-96-2 |
| structural formula | C21H30O3 |
| molecular weight | 330.46 |
| EINECS | 200-699-4 |
| melting point | 276°C |
| boiling point | 407.89°C (rough estimate) |
| Acidity coefficient (pKa) | 13.03±0.60(Predicted) |
| density | 1.0998 (rough estimate) |
| Storage condition | Sealed in dry,Room Temperature |
What is the use and efficacy of Hydroxyprogesterone ?
Hydroxyprogesterone is widely used in many fields in medicine. In the field of gynecology, it can be used to treat infertility and luteal insufficiency, which can simulate the effect of progesterone, promote endometrial hyperplasia, support the implantation of fertilized eggs and maintain pregnancy.
Hydroxyprogesterone powder may be recommended under certain circumstances. In addition, it is also widely used in prenatal examination and diagnosis of some diseases during pregnancy, such as evaluating the risk of premature delivery and screening for congenital adrenal hyperplasia.
By detecting the level of 17α-Hydroxyprogesterone in pregnant women, we can evaluate whether the fetus has the risk of premature delivery or the potential risk of congenital adrenal hyperplasia.
How is Hydroxyprogesterone's research going ?
In vitro study
Hydroxyprogesterone powder is a progesterone receptor agonist similar to progesterone, although its effect is weak. It is also a chemical intermediate in the biosynthesis of hormones.
In vivo study
It is an effective steroid inducer of GVBD. Studies have shown that obesity in non-diabetic men aged 18-49 is related to the decrease of serum Hydroxyprogesterone level.
Product Specification
| Items | Specifications | Results | ||
| Appearance | white to almost white powder | white powder | ||
| Assay | 96%-101% | 98.28% | ||
| Loss on Drying | ≤5.0% | 0.07% | ||
| Residue on Ignition | ≤0.1% | 0.04% | ||
| Heavy metals | ≤10ppm | 4.5ppm | ||
| As | ≤1ppm | ≤1ppm | ||
| Pb | ≤1ppm | ≤1ppm | ||
| Cd | ≤1ppm | ≤1ppm | ||
| Hg | ≤0.1ppm | ≤0.1ppm | ||
| Total Plate count | ≤1000CFU/g | <10CFU/g | ||
| Yeast &Mould | ≤100CFU/g | <10CFU/g | ||
| Escherichia Coli | Negative | Negative | ||
| P.aeruginosa | Negative | Negative | ||
| S.aureus | Negative | Negative | ||
| Salmonella | Negative | Negative | ||
| Conclusion: The test results are conformed to the in-house specification | ||||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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