Desogestrel API Powder CAS 54024-22-5
Product Name:Desogestrel API powder
CAS NO.:54024-22-5
Molecular Formula:C22H30O
EINECS.NO:258-929-4
Synonym:Desogestrel(50mg);DESTODENE;Desogestrelforsystemsuitability,EuropeanPharmacopoeia(EP)ReferenceStandard
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Description
What is Desogestrel API powder ?
Desogestrel is an active ingredient of highly selective progestogen products, which is a white or white-like crystalline powder. Its production needs multi-step organic synthesis, oxidation, dehydration, reduction and other key steps, as well as strict purification processes (crystallization, chromatographic separation, etc). At present,Desogestrel API powder is widely used in the global family planning field, and it is an important active ingredient with high efficiency and tolerance in female contraceptive products.
| Product name | Desogestrel API powder |
| CAS | 54024-22-5 |
| Molecular formula | C22H30O |
| Molecular weight | 310.47 |
| EINECS | 258-929-4 |
| Boiling point | 109-110°C |
| boiling point | 390.62°C (rough estimate) |
| Density | 1.0169 (rough estimate) |
| The acidity coefficient (PKA) | 13.07±0.40(Predicted) |
| Storage condition | Sealed in dry,Room Temperature |
What is the action mechanism of Desogestrel API powder ?
The core of the action mechanism of Desogestrel API is to mimic human natural progesterone and prevent pregnancy through multi-link synergy. Because it is a highly selective progesterone receptor agonist, it can avoid androgen-like side effects while effectively preventing contraception. Specifically, it can be divided into three key links:
1. Inhibition of ovulation (the core mechanism)
The normal ovulation of women depends on the precise control of hypothalamus-pituitary-ovary axis: the hypothalamus secretes gonadotropin-releasing hormone → the pituitary secretes follicle-stimulating hormone and luteinizing hormone → promotes follicular development and triggers ovulation. Desogestrel API powder will bind to progesterone receptors in hypothalamus and pituitary with high affinity, so that follicles cannot mature and rupture, thus directly preventing the ovulation. This is the primary link of its contraceptive function.
2. Change the characteristics of cervical mucus (blocking sperm penetration)
Under normal circumstances, women's cervical mucus during ovulation is thin, large in quantity and good in drawing degree, which is beneficial for sperm to penetrate into the uterus. It will thicken the cervical mucus, reduce the amount and form a "mucus plug", which will hinder the swimming and penetration of sperm. Even if a small amount of sperm enters, it is difficult to reach the fallopian tube and combine with the egg.
3. Affect the endometrial environment (inhibit implantation)
The fertilized egg needs to attach to the endometrium with appropriate thickness and abundant blood supply in order to successfully implant. It will change the shape and function of the endometrium: it will make the endometrial glands underdeveloped and the stromal decidualization incomplete, which will lead to the endometrium being "not suitable for fertilized eggs to implant"-even if eggs are fertilized, they will not grow stably in the uterus.
Key advantages: high selectivity and less side effects.
It has almost no affinity for androgen receptor and will not activate androgen-mediated metabolic pathway, so Desogestrel API powder can avoid androgen-related side effects such as weight gain, acne, hirsutism, etc., while retaining the contraceptive activity of progesterone, and is a milder and more tolerant contraceptive component.
In short, Desogestrel API realizes efficient contraception through the triple insurance of "inhibiting ovulation+preventing sperm+preventing implantation", and makes the contraceptive process more comfortable because of its high selectivity, which is why it has become the core raw material of modern contraceptive products.
Product Specification
| Items | Specifications | Results |
|
Appearance |
white to off-white crystalline powder | Complies |
| Assay (HPLC) | ≥98.0% | 99.61% |
| Water Content | ≤ 0.50% | 0.31% |
|
Heavy Metals |
≤10ppm |
<10ppm |
|
Microbial Limit |
≤20ppm |
<20ppm |
| Yeast &Mold | ≤50cfu/g | <10cfu/g |
| Coliforms | ≤3cfu/g | <3cfu/g |
| E.Coli | Negative/10g | Negative |
| Salmonella | Negative/25g | Negative |
| S.aureus | Negative/25g | Negative |
| Conclusion: The test results are conformed to the in-house specification | ||
How and where to buy Desogestrel API powder wholesale ?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details , Click email: sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details , Click email : sales7@faithfulbio.com Now.
FAQ:
Q1:What are the transportation modes of Desogestrel API powder ?
A1:Mode of transportation: According to the order quantity and customer demand, you can choose air transportation (express delivery/freight), sea transportation (whole container/LCL) or land transportation (neighboring countries only), and the transportation should be treated as "fragile, moisture-proof and light-proof" goods. Logistics service: We have cooperation with DHL, FedEx, EMS and other express delivery services.
Q2:Do you support customized services? Such as adjusting particle size, crystal form or packaging specifications?
A2:Yes, we support limited customization services (based on process feasibility assessment): Physical specifications: particle size distribution and crystal form can be adjusted; Packaging specifications: In addition to the conventional 1kg/5kg/25kg packaging, small specifications (such as 100g aluminum foil bags) or large specifications can be customized.
Q3: Besides the Desogestrel API, do you supply other steroid hormone APIs (such as Drospirenone and Gestodene)? Can you provide one-stop procurement ?
A3:Yes, we support limited customization services (based on process feasibility assessment): Physical specifications: particle size distribution and crystal form can be adjusted; Packaging specifications: In addition to the conventional 1kg/5kg/25kg packaging, small specifications (such as 100g aluminum foil bags) or large specifications can be customized.
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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