17a-estradiol CAS 57-91-0
Product Name:17a-estradiol
CAS NO.:57-91-0
Molecular Formula:C18H24O2
EINECS.NO:200-354-8
Synonym:1,3,5-estratriene-3,17-alpha-diol;1,3,5-Estratriene-3,17alpha-diol;17alpha-Oestradiol;3,17alpha-Dihydroxyestra-1,3,5(10)-triene;3,17alpha-Dihydroxyoestra-1,3,5(10)-triene;5(10)-triene-3,17-diol,(17-alpha)-estra-3;epiestradial
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Description
What is 17a-estradiol ?
17a-estradiol is a natural estrogen and a stereoisomer of β-Estradiol, the main estrogen with the strongest biological activity in human body.The most important value of Estradiol lies in its local antagonism to male effects, while avoiding the systemic side effects of powerful estrogen. This makes it a unique and practical ingredient in the field of external treatment of alopecia.
| Product name | 17a-estradiol |
| CAS | 57-91-0 |
| structural formula | C18H24O2 |
| molecular weight | 272.39 |
| EINECS | 200-354-8 |
| Melting point | 176-180 °C(lit.) |
| boiling point | 355.44°C (rough estimate) |
| density | 1.0708 (rough estimate) |
| Acidity coefficient (pKa) | 10.27±0.60(Predicted) |
| Storage condition | Sealed in dry,Room Temperature |
What is the biological activity and function of 17a-estradiol ?
Because of its weak receptor binding ability, it hardly shows systemic estrogen effect (such as affecting the development of uterus and breast or regulating menstrual cycle). However, 17a-estradiol may work locally (especially in skin and hair follicles) through other mechanisms:
Local anti-oxidation: it may reduce the conversion of androgen to more active substances by inhibiting 5-alpha reduce.
In scalp hair follicles and other parts, epiestradial may antagonize the effect of androgen by competing with androgen for receptors. This is the theoretical basis of its application in the treatment of androgenetic alopecia.
What are the main uses of 17a-estradiol ?
Because of its local effectiveness and extremely low activity after systemic absorption, it is very suitable for external use and has high safety.
1. Hair growth therapy: 17a-estradiol is the key component of many over-the-counter or prescription hair growth solutions (often compounded with Minoxidil) and is used to treat androgenetic alopecia in men and women. It helps to prevent the miniaturization of hair follicles and promote hair growth through the above-mentioned mechanism of local antagonism to male effect.
2. Skin care: Estradiol is occasionally added to high-end skin care products or lotions, claiming anti-aging, anti-oxidation and improving skin quality. However, its exact effect and position in skin care products still need more scientific evidence to support.
Product Specification
| Items | Specifications | Results | ||
|
Appearance |
White powder | White powder | ||
|
Assay(on the dried basis) |
97.0%-103.0% |
99.62% |
||
|
Identification |
Positive Reaction |
Positive Reaction |
||
|
Loss On Drying |
≤0.5% |
0.13% |
||
|
Residue On Ignition |
≤0.1% |
0.02% |
||
|
Heavy Metals |
≤20ppm |
<20ppm |
||
|
Clarity Of Solution |
Conform To Standard |
Complies |
||
|
Microbial Limit |
≤20ppm |
<20ppm |
||
| Conclusion: The test results are conformed to the in-house specification | ||||
How and where to buy 17a-estradiol wholesale ?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details , Click email: sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details , Click email : sales7@faithfulbio.com Now.
FAQ:
Q1:Both men and women use 17a-estradiol?
A1: Yes. It is one of the few local estrogens that have been studied to treat androgenetic alopecia in both men and women. Because of its high safety, the risk to male users is far lower than other estrogen products.
Q2: What's the difference between it and minoxidil? Can I use it together ?
A2: The mechanisms of the two are completely different, and the combined use is usually better, which is a common compound strategy.
Q3: Can you send me your price list / catalog ?
A3: Of course! In order to give you the most accurate quotation, could you please tell me which products or categories you are most interested in? Or, do you have a specific target market? So I can screen the most suitable products and standards for you.
Disclaimer : The articles published on this website are mainly used for academic research and technical discussions, which is dialectical and does not mean that this website agrees with all of its views. Please screen carefully. If there is any infringement or other dispute, please contact the administrator. We are not responsible for the consequences of using the information and services on this website.
Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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