Spermidine Powder CAS 124-20-9

How to extract spermidine powder?

Product Specification

Conclusion：Conform with enterprise specification .

Where is spermidine powder usually used?

Spermidine is a low molecular weight nitrogen-containing base widely present in organisms, involved in regulating many physiological and biochemical processes of plant growth and development, including seed germination, adventitious root formation, microbial symbiosis, and resistance to abiotic stress. Here are some specific uses of spermidine:
1. Improve plant resistance to abiotic stress: Exogenous spermidine can significantly enhance plant resistance to abiotic stress such as drought, salt damage, high and low temperatures, floods, and heavy metals. Research has shown that the mechanism by which spermidine participates in regulating plant stress resistance is mainly as a stress transmission signal, stimulating plant resistance mechanisms at the physiological and biochemical levels.
2. Improve antioxidant enzyme activity and proline content: Studies have found that exogenous spermidine can effectively enhance the antioxidant enzyme activity and proline content of white clover under water stress, thereby improving its antioxidant capacity and osmotic regulation function.
3. Relieve oxidative damage: Exogenous spermidine can alleviate oxidative damage caused by salt alkali stress, improve chloroplast structural integrity, and enhance tomato resistance to salt alkali stress by regulating chlorophyll metabolism and antioxidant system.
4. Regulating the relative water content, ion balance, and photosynthesis of plant leaves: Spermidine can also regulate the relative water content, ion balance, and photosynthesis of plant leaves under abiotic stress.
5. As a selective inhibitor of nNOS (neural nitric oxide synthase): Spermidine trihydrochloride (Spermidine) is a selective inhibitor of nNOS used in scientific research by professionals.
In summary, spermidine has a wide range of applications in plant science and medical research, particularly in the study of plant stress resistance and signal transduction.

What are the effects of spermidine powder ?

Spermidine is a naturally occurring polyamine compound widely found in plants, animals, and microorganisms. In recent years, spermidine has received increasing attention due to its potential benefits in health and physiological functions. Here are some of the main effects of Spermidine:
1. Promote cellular autophagy: It plays an important role in the process of cellular autophagy. As age increases, autophagy ability gradually decreases, leading to the accumulation of intracellular damaging substances. Supplementing with Spermidine can activate autophagy, promote intracellular clearance and regeneration, thereby helping to delay aging.
2. Activation of mTOR signaling pathway: It can activate the mTOR signaling pathway, which is a key signaling hub in cells and plays a central role in regulating protein synthesis. By activating mTOR, It can promote muscle protein synthesis and maintain muscle mass.
3. Inhibit muscle protein breakdown: It can inhibit muscle protein breakdown by regulating the ubiquitin proteasome system (UPS) and autophagy lysosome pathway (ALP). It can inhibit the activity of some E3 ubiquitin ligases, reduce the ubiquitination of muscle proteins, and thus lower the rate of muscle protein breakdown.
4. Promote satellite cell function: It can activate the proliferation and differentiation of satellite cells, which play a crucial role in muscle growth and repair processes. By promoting the function of satellite cells, Spermidine helps to increase muscle mass and promote muscle repair.
5. Improve sleep quality: It may affect sleep cycles by regulating the balance of neurotransmitters. Research has shown that Spermidine can promote the synthesis of gamma aminobutyric acid (GABA), an important inhibitory neurotransmitter that helps relax the nervous system and promote sleep.
6. Extending lifespan and anti-aging: It can maintain telomere length, and telomere shortening and damage are recognized as causes of cellular aging and senescence. In addition, Spermidine powder can stabilize mitochondrial function, fight inflammation, and maintain the youthfulness of stem cells, all of which contribute to prolonging lifespan and anti-aging.
7. Protecting the heart and regulating metabolism: It can stabilize mitochondria and protect the heart; Can regulate metabolism, lower blood lipids, lower blood sugar, and lose weight.
8. Protecting nerves and preventing diseases: It can protect nerves, improve memory, prevent and treat Alzheimer's disease (AD); Can antagonize mutations, prevent and treat tumors; Can prevent bone loss, prevent osteoporosis, and so on.
It should be noted that although Spermidine has shown many potential health benefits, scientific research is still ongoing, and more studies on its mechanism of action and clinical applications are underway.