Salidroside Powder CAS 10338-51-9

Product Specification

Where is Salidroside powder usually used?

Salidroside Powder is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It has various applications in scientific research as a prolyl peptidase inhibitor. Common uses include the following:
1. Protect the liver: Salidroside can protect liver tissue from oxidative stress caused by D-galactosamine and LPS.
2. Antitumor: Salidroside can cause G1 and G2 phase arrest in different cancer cell lines, while reducing CDK4, cyclinD1, cyclinB1, and Cdc2, and upregulating the levels of p27 (Kip1) and p21 (Cip1). Salidroside concentration and time-dependent inhibition of the growth of various human cancer cell lines.
3. Neuroprotection: Salidroside activates the PI3K/Akt pathway, leading to a protective effect against MPP (+) - induced apoptosis in PC12 cells, which can be used to treat Parkinson's disease (PD). By activating the ERK1/2 pathway and inhibiting caspase-3 activation, Salidroside can also reduce the loss of cell viability and apoptotic cell death induced by H2O2 stimulation in cultured NGF differentiated PC12 cells.
4. Regulating gut microbiota: Salidroside can regulate gut microbiota, thereby improving gut health.
It should be noted that Salidroside Powder is typically used for scientific research and is not suitable for personal use. When using, relevant operating guidelines and safety regulations should be followed.

What are the effects of Salidroside powder?

Salidroside powder, It has multiple potential biological effects, including:
1. Antioxidant effect: Salidroside can protect liver tissue from oxidative stress damage, such as damage caused by D-galactosamine and LPS.
2. Antitumor effect: Salidroside can cause G1 and G2 phase arrest in different cancer cell lines, reduce the levels of CDK4, cyclinD1, cyclinB1, and Cdc2, and upregulate the levels of p27 (Kip1) and p21 (Cip1). These effects suggest that Salidroside may inhibit the growth of cancer cells by affecting the cell cycle and apoptosis pathways.
3. Neuroprotective effect: Salidroside activates the PI3K/Akt pathway, which has a protective effect on MPP (+) - induced apoptosis of PC12 cells, indicating that it may be beneficial for the treatment of Parkinson's disease (PD). In addition, by activating the ERK1/2 pathway and inhibiting caspase-3 activation, Salidroside can also reduce the loss of cell viability and apoptotic cell death induced by H2O2 stimulation in cultured NGF differentiated PC12 cells.
4. Regulating gut microbiota: Studies have shown that Salidroside can alleviate symptoms of ulcerative colitis by regulating the gut microbiota.
It should be noted that although the above studies have shown multiple potential benefits of Salidroside powder, these effects may be influenced by various factors such as dosage, administration route, and individual differences. Therefore, in practical applications, it should be used under the guidance of professionals and taking into account individual circumstances.