Rutin Powder CAS 153-18-4

Rutin is the rutin glycoside of quercetin, a flavonol compound extracted from plants. It is found in various plants, including Sophora japonica L., a leguminous plant, with a content of over 20% in its flower buds. It is the main raw material for extracting rutin in China's pharmaceutical industry. High quality Rutin powder can decompose with water when exposed to strong acidity and alkalinity. It is unstable in color in alkaline foods and has antioxidant capacity. Ethanol can improve the light resistance of pigment preparations, prevent the gradual disappearance or change of fragrance, and enhance their antioxidant capacity when combined with vitamin E.

What is the relationship between rutin and quercetin?

Rutin powder is a glycoside of the flavonoid quercetin. It comes from a combination of quercetin and a disaccharide called rutin. In fact, it is sometimes referred to as purple quercetin.
Quercetin is also a flavonoid antioxidant found in plants, including berries, broccoli, and leafy vegetables. Quercetin is taken in capsule or tablet form to combat oxidative stress, reduce inflammation, improve cardiovascular health, promote blood circulation, and reverse cognitive impairment.
Both supplements can be widely used. They exist in various forms, and the amount of active ingredients varies depending on the product.

What are the pharmacological effects of rutin?

Rutin, also known as vitamin P, is a bioflavonoid, which exists in some foods, including apples, figs, most citrus fruits, buckwheat and green tea. Like all flavonoids, it has powerful antioxidant and anti-inflammatory effects. Therefore, it is often used as a drug to strengthen blood vessels, improve blood circulation, lower cholesterol and relieve arthritis symptoms. In addition, rutin is also famous for promoting collagen production and helping the body to absorb vitamin C healthily.
1. Promote heart health
Speaking of heart health, recent research shows that rutin helps to maintain vascular elasticity, reduce vascular fragility, reduce capillary permeability and prevent complications caused by hypertension.

An animal study published in Experimental and Therapeutic Medicine in 2018 found that it inhibits heart disease by signaling specific protein kinases called ERK1/2 and Akt. The most effective dose of rutin for pigs with coronary heart disease is 45 mg/kg body weight. Rutin administration can reduce the size of dead heart tissue in pigs with heart disease, inhibit urine protein concentration and improve blood circulation.

Another animal study published in Human and Experimental Toxicology in 2014 found that rutin and quercetin treatment can reduce the cardiovascular effects of high-salt diet on hypertensive rats. In fact, the combination of these bioflavonoids is more effective than nifedipine, a drug used to treat hypertension and chest pain.

2. Relieve arthritis symptoms
Animal studies show that this antioxidant has the ability to inhibit acute and chronic inflammation. This makes it a potential natural treatment for arthritis. Russian researchers have found that rutin can reduce the excessive production of free radicals in rheumatoid arthritis. They come to the conclusion that it can be considered as a useful adjuvant.

In addition, a laboratory study published in Pharmacology in 2017 found that rutin improved the formation of joint surface tissue, improved cartilage and bone erosion, and reduced inflammation. This shows that it has protective effect on rheumatoid arthritis.

3. Fight cancer
Rutin powder can be used as an anticancer drug because of its antioxidant and anti-inflammatory effects. It has also been proved that it can induce apoptosis or cancer cell death, and shows anti-tumor effect. Flavonoids have been used to sensitize cancer cells to anticancer drugs and reverse the drug resistance of patients receiving cancer treatment.

A large number of studies involving humans, rodents and cells show that this antioxidant can reduce tumor size, increase cancer cell death and prolong survival time. A scientific review discussing the pharmacological potential of rutin found that flavonoids have anticancer effects on many different cancers, including leukemia, colon cancer, colorectal cancer, melanoma, liver cancer and lung cancer.

A laboratory study published in Phytotherapy Research found that this phytochemical can be used as a chemosensitizer for two human breast cancer cell lines. Rutin significantly improved the anticancer activity of anticancer drugs, and helped to successfully prevent the fine.

Why can long-term use of this product enhance physical fitness?

Rutin belonging to vitamin P is the glycoside of dehydroflavanone. As a hydrogen transporter, it may be involved in the role of oxidoreductase in the body, which can affect the activity of thyroid and prevent adrenaline from oxidation. It can enhance the function of vitamin C and promote its accumulation in the body. It can maintain the elasticity of blood vessels, reduce their permeability and reduce their brittleness. We know that hyaluronic acid is a matrix component in the intercellular substance of capillary wall. When it is hydrolyzed by hyaluronidase, it will reduce the resistance of capillary, increase the permeability and brittleness, and easily cause bleeding. Rutin can inhibit hyaluronidase and prevent the hydrolysis of hyaluronic acid, thus enhancing the resistance of capillaries, reducing their permeability and brittleness, and maintaining and restoring the normal elasticity of capillaries. This function is very necessary to keep the blood vessels unblocked, and it is also the key to ensure the microcirculation of the body.
Rutin is a flavonoid extracted from plants and rutin glycoside of quercetin, a flavonol compound. It can not only reduce the permeability and brittleness of capillaries, but also maintain and restore the normal elasticity of capillaries. It has good anti-radiation and anti-free radical effects on the skin, and has a strong absorption effect on ultraviolet rays and X-rays. According to relevant research, when 10% rutin is added to the natural sunscreen, the absorption rate of ultraviolet rays is as high as 98%, which has an obvious effect of scavenging cell active oxygen free radicals. This is very important for the study of radiation resistance of cells. According to scientists' research, genes in biological cells can be easily tampered with after long-term exposure to micro-radiation, which will lead to various cell abnormalities and accelerate the process of organism aging. Based on this, scientists believe that all kinds of micro-radiation in our living environment can not directly harm us, but it will subtly change our cell activity and accelerate the deterioration of the environment on which the body depends. Like all flavonoids, rutin powder, a bioflavonoid, has powerful anti-oxidation and anti-radiation effects, which is beneficial to the overall cell health of the heart, brain, blood vessels and skin.

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