Product description
Thymulin acetate is the nonapeptide secreted by its epithelial cells. Thymulin is composed of nine amino acids, Glu - Ala - Lys - Ser - Gln - Gly - Gly - Ser - Asn. A large number of in vivo and in vitro experimental studies have proved that Thymulin is an important factor promoting the differentiation of lymphocytes and enhancing their functions. It has the functions of stimulating the activity of immune cells, regulating immune function, and enhancing non-specific cellular immunity of the body. Moreover, it has the advantages of small molecular weight, non-toxicity, no antigenicity, and no allergic reactions.
Thymulin, as a new and safe immunosuppressant, is widely used in the prevention and treatment of human and animal diseases and is a biological product with great development and application prospects. It is applicable to primary and secondary immune deficiency diseases, diseases caused by immune dysfunction, adjuvant treatment of tumors, aplastic anemia, acute and chronic viral hepatitis, and can also be used for lupus erythematosus, rheumatoid arthritis, allergic asthma, etc.
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COA
| ltems | Standard | Results |
| Appearance | White powder | Conforms |
| MS(ESI) | Conforms | Conforms |
| Purity(HPLC) | ≥98.0% | 99.19% |
| Water Content (Karl Fischer) | ≤10.0% | 2.30% |
| Peptide Content(N%) | ≥80.0% | 94.6% |
| Mass Balance | 95.0~105.0% | Conforms |
| Conclusion | Conform with enterprise specification | |
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Density: 1.417 g/cm ³
Boiling point: 1658.9 ° C at 760 mmHg
Molecular formula: C33H54N12O15
Molecular weight: 858.85300
Flash point: 957.1 ° C
Precise mass: 858.38300
PSA 451.86000
What stimulates the release of Thymulin Acetate?
IL-1 was shown to stimulate the secretion of Thymulin acetate as measured both by its ability to stimulate induction of IL-2 receptor-positive lymphocytes from human peripheral blood lymphocytes and by the azathioprine-sensitive rosette assay.
What is the function of Thymulin Acetate?
Take home message: Thymulin has a selective immunomodulatory effect, enhancing anti-inflammatory and inhibiting pro-inflammatory cytokines. It suppresses p38 (implicated in glucocorticoid-resistance) and inhibits NF-kappaB activation, which has an important pathogenic role in several lung diseases.
Is Thymulin Acetate the same as thymalin?
Thymalin is a synthetic version of Thymulin, and was originally derived from calf thymus. Thymalin exhibits immune and geroprotective effects by normalizing differentiation, proliferation, and reducing apoptosis of lymphoid cells, thereby activating cellular immunity and regeneration processes.
Key Functions of Thymulin Acetate
T-cell Differentiation:
Thymulin is essential for the maturation and differentiation of T-cells, both within the thymus and in peripheral lymphoid tissues.
Immune Modulation:
It helps regulate the immune system by influencing the balance of different T-cell subsets and potentially affecting cytokine production.
Anti-inflammatory Effects:
Thymulin can suppress the production of pro-inflammatory cytokines and inhibit inflammatory pathways like NF-kappaB, which are involved in various inflammatory diseases.
Pain Modulation:
Recent research suggests thymulin has anti-nociceptive effects, potentially reducing pain perception and inflammation, especially in neurological contexts.
Communication between Systems:
Thymulin may act as a signaling molecule for interactions between the immune, endocrine, and nervous systems, potentially influencing the brain and other areas.
Circadian Rhythm:
Thymulin acetate release in the blood exhibits a circadian rhythm, suggesting its involvement in the body's daily rhythms.
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why choose us
Our Factory
Package
Shipping Methods
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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