What is Dermorphin Peptide?
Xi'an Faithful BioTech Co., Ltd. is situated in Xi'an, the birthplace of the ancient Silk Road. Leveraging the city's mature logistics network and abundant fine chemical industrial resources, our enterprise has grown into an integrated fine chemical provider that delivers products to global partners. Dermorphin Peptide, CAS No. 77614-16-5, is a natural heptapeptide isolated in 1981 by a research team from the skin secretions of the South American wax monkey leaf frog and the bicolor leaf frog. Its complete amino acid sequence is H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂, its molecular formula is C₄₀H₅₀N₈O₁₀, and its molecular weight is 802.87. It is a white to light off-white powder with a purity generally exceeding 96%. The most distinctive structural feature of this substance is the presence of a D-alanine residue at the second position of its sequence. Most vertebrate polypeptides in nature contain only L-type amino acids; this unique D-configuration forms a spatial barrier, significantly reducing the degradation efficiency of the molecule by various enzymes, thus endowing it with long-lasting and stable biological activity. Simultaneously, the terminal amidation modification further enhances its ability to bind to receptors in the body.
Application of Dermorphin Peptide
Dermorphin's core applications are concentrated in basic scientific research, and it is widely used in experiments in neurophysiology, receptor molecular interaction, and somatic sensory signal transduction. Researchers use various animal models to explore various somatic discomfort-related transmission pathways and receptor response patterns based on this substance. At the same time, it is used as a blueprint to modify and derive new peptide structures, explore optimization ideas for active peptide molecules, and early related observation experiments have also verified its outstanding performance in relieving somatic discomfort, making it valuable for research on related optimization materials.
COA
| Test Item | Specification | Test Result |
| Appearance | White powder | White powder |
| HPLC Purity(RP-HPLC,220nm) | ≥98.0% | 99.42% |
| Mass Spectrometry Identity | Observed MW matches theoretical MW±0.1 Da |
Confirmed,MW=802.85 |
| Single Unknown Impurity | ≤1.0% | 0.31% |
| Total Impurities | ≤2.0% | 0.58% |
| Water Content (Karl Fischer) | ≤3.0% | 1.16% |
| Residual Trifluoroacetate | ≤0.5% | 0.22% |
| Endotoxin Level | ≤10 EU/mg | <0.5 EU/mg |
| Conclusion | Conform with enterprise specification | |
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Molecular Formula: C40H50N8O10
Molecular Weight: 802.87
Exact Mass: 802.36500
PSA: 314.05000
LogP: 3.98630
InChIKey FHZPGIUBXYVUOY-VWGYHWLBSA-N
Mechanism of action of Dermorphin
Unique Amino Acid Structure Enhances Stability
The peptide chain contains D-alanine at position 2, unlike common L-type amino acids. This unique spatial configuration forms a structural barrier, reducing the breakdown of the peptide chain by proteases in the body and prolonging the duration of molecule activity in the biological environment.
Regulating Sensory Signal Transduction
After the receptor is activated by this substance, it initiates intracellular signal transduction pathways, regulates the efficiency of signal transmission between nerve cells, alters the intensity of signals related to bodily discomfort, and produces significant soothing physiological responses.
Central Nervous System Activity Amplification Effect
When the molecule acts on relevant areas of the central nervous system, the physiological effects of receptor activation are significantly enhanced, exhibiting several times or even thousands of times greater biological activity compared to its effect on peripheral tissues.
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Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. What class of substances does Dermorphin belong to, and what is its peptide chain length?
Dermorphin Peptide is a natural, bioactive heptapeptide, with its molecule composed of 7 amino acids.
02. What is the current mainstream method for obtaining Dermorphin?
It is no longer extracted from frog skin; solid-phase peptide synthesis is commonly used in both laboratory and industrial settings.
03. What physiological effects does Dermorphin produce after activating its corresponding receptor?
It regulates signal transmission between nerves, weakens signals related to bodily discomfort, and brings about a significant soothing effect.
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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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