Lemotigine is a novel phenyltriazine based antiepileptic product commonly used in the treatment of refractory epilepsy and as an emotional stabilizer for type I bipolar disorder. The color of pure Lamotrigine powder is white or off white with a slight yellow tint. Crystallize in isopropanol and easily soluble in organic solvents such as benzene, toluene, and hot ethanol.
| Molecular formula |
|
|
|
Item |
Standard |
Test Results |
|
Appearance |
White powder |
Conforms |
|
Identification (IR) |
Concordant with reference spectrum |
Conforms |
|
Assay |
≥99.0% |
99.2% |
|
Water |
<2.0% |
0.4% |
|
Residual solvent |
<1.0% |
0.2% |
|
Heavy Metals |
≤15 |
10 |
|
Loss on Drying |
≤0.3% |
0.04% |
|
Residue on Ignition |
≤0.3% |
0.08% |
|
Chromatographic purity |
Meets the requirements |
Conforms |
|
Organic volatile impurities |
Meets the requirements |
Conforms |
|
Microbial assessment |
Compliance with indicators |
Conforms |
|
BSE |
not detected |
not detected |
|
GMO |
not detected |
not detected |
|
Allergen |
not detected |
not detected |
|
Radiation |
not detected |
not detected |
What are the pharmacological effects of this product?
Lemotigine is a voltage dependent sodium channel blocker, whose mechanism of action is to block presynaptic membrane voltage-gated sodium channels and inhibit pathological glutamate release, thereby inhibiting glutamate induced action potential bursts and stabilizing neuronal cell membranes. For example, Hot sales Lamotrigine powder can exert the following mechanisms in response to epilepsy: ① Inhibit voltage dependent type IIa Na+channels, stabilize cell membranes, and inhibit abnormal neuronal cell discharges; ② Stabilize the presynaptic membrane and inhibit the release of excitatory neurotransmitters, especially glutamate; ③ Inhibit voltage-gated calcium channels.
What is the clinical efficacy of this product?
Lamotrigine powder can inhibit glutamate release, which may control the disease by inhibiting sodium, potassium and calcium currents. When this product is used clinically to treat bipolar depression, it can be quickly and completely absorbed in the intestine, and there is no obvious metabolic problem, and the induction effect on liver drug enzymes and self-induction is small, so this product has no adverse effect on patients' cognitive function, and has the effect of improving cognitive function; In the clinical treatment of epilepsy, especially intractable partial epilepsy, its role is also safe and effective.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Lamotrigine powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
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