Product Introduction
Escitalopram oxalate powder is a white or off-white powder, which is easily soluble in methanol and dimethyl sulfoxide, soluble in physiological saline, slightly soluble in water and ethanol, slightly soluble in ethyl acetate, and insoluble in heptane. It is the S-isomer metabolite of citalopram and the main pharmacologically active component of citalopram. Its chemical name is (S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate.
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| Escitalopram oxalate powder Picture | Escitalopram oxalate powder MF |
Product Application
Escitalopram oxalate powder is the active isomer of citalopram (S-citalopram), which has a highly selective inhibitory effect on the reabsorption of 5-hydroxytryptamine (5-HT) and has little effect on the reabsorption of norepinephrine and dopamine. It increases the concentration of 5-HT in the synaptic cleft by preventing the reabsorption of 5-HT, thereby producing an antidepressant effect. It is mainly suitable for the treatment of severe depression.
OBJECTIVE To establish an HPLC method and potentiometric titration method for the determination of escitalopram oxalate and its related substances for quality control. METHODS Chromatography was carried out on an Inertsil C8 column (4.6 mm×250 mm,5 μm), using the mobile phase of acetonitrile-acetate buffer solution (containing 1 g sodium acetate and 6 mL triethylamine in 1 000 mL of water, pH adjusted to 4.6 with acetic acid ) (30∶70) at the flow rate of 1.0 mL·min-1.
The detection was carried out with a UV detector at 239 nm, and the column temperature was 40 ℃. The determination was also performed by potentiometric titration, using glacial acetic acid as solvent and 0.1 mol·L-1 perchloric acid as titrant. RESULTS Escitalopram oxalate and the related substances were separated completely under the above chromatographic conditions. The standard curve of escitalopram oxalate was linear within the range of 10-800 μg·mL-1, with the correlation coefficient of 0.999 9, and limit of detection of 0.94 ng. The intra-day and inter-day RSDs were 0.39%(n=6) and 0.77%(n=5), respectivley.
Product Specification
| Item | Test Standard | Testing Result |
| Assay | 99% | Complies |
| Apperence | White Powder | Complies |
| Particle Size | 100% pass 80 mesh | Complies |
| Oder | Characteristic | Complies |
| Taste | Characteristic | Complies |
| Loss on Drying | ≤5.0% | 2.20% |
| Residue on Ignition | ≤0.1% | 0.05% |
| Residual | ≤0.1% | Complies |
| Residual Ethanol | ≤0.5% | Complies |
| Heave Mentals | ≤10ppm | Complies |
| Na | ≤0.1% | <0.1% |
| Pb | ≤3 ppm | Complies |
| Total Plate | <1000CFU/g | Complies |
| Yeast & Mold | <100 CFU /g | Complies |
| E. Coli | Negative | Complies |
| Salmonella | Negative | Complies |
| Conclusion：Conform with enterprise specification . | ||
How To Obtain Samples Escitalopram oxalate powder?
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The Best Escitalopram oxalate powder Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Escitalopram oxalate powder?
Faithfulbio specialize in Escitalopram oxalate powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Escitalopram oxalate powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Escitalopram oxalate powder?
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