Vitamin K1 Powder CAS 84-80-0

Vitamin K1 Powder CAS 84-80-0

Product Name:Vitamin K1
CAS NO.: 84-80-0
MF NO.:C31H46O2
EINECS NO.:201-564-2
Synonym:Vitamin K1;Phytomenadione;PHYTONADIONE;kativn;Kephton;PHYLLOQUINONE;VK1;Kaywan;Kephton;Kinadion;K-Ject;Orakay;Phylloquinone-d3
Test Method:HPLC/UV
MOQ & Package: 10g,100g,1kg etc Sub-package
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Send Inquiry
Description

Vitamin K is oily liquid or solid, insoluble in water, soluble in organic solvents such as oil and ether, with stable chemical properties, heat and acid resistance, but easily decomposed by alkali and ultraviolet rays. Vitamin K, which the human body needs little, but the newborn is easy to lack, is an important vitamin to promote normal blood coagulation and bone growth.
Vitamin K can be divided into two categories, both of which are derivatives of 2-Methyl-1,4-naphthoquinone. One category is fat-soluble vitamins, such as vitamin K1 and vitamin K2, in which vitamin K1 is yellow oil and K2 is light yellow crystal, which have heat resistance, but are easily damaged by ultraviolet radiation, so they should be stored away from light. The other is water-soluble vitamins, which are synthesized artificially, namely vitamins K3 and K4. However, the most important things in daily life are vitamin K1 powder and K2.

structural formula

84-80-0 Vitamin K1

Items

Standard

Results

Identification

1 Color reaction

2 Retention Time

1 Positive

2 The retention time of the major peak in the test solution is the same as that of the standard preparation.

Positive

Conform

Acidity

≤1.0 ml

0.03 ml

Assay

≥95.1%

≥600 IU/g

95.8%

609 IU/g

Appearance

The liquid forms are clear,slight

brownish to slight yellow,viscous oily

Conform

Benzo(a)Pyrene

≤2 ppb

<2 ppb

Solvent residue-Hexane

≤290 ppm

1 ppm

Heavy Metals

Lead ≤1 mg/kg

<1 mg/kg

 

Arsenic ≤1 mg/kg

<1 mg/kg

 

Cadmium ≤1 mg/kg

<1 mg/kg

 

Mercury ≤0.1 mg/kg

<0.1 mg/kg

Microbiology

Aerobic Plate Count ≤1000(cfu/g)

<10(cfu/g)

 

Yeast and Molds ≤100(cfu/g)

<10(cfu/g)

 

Escherichia Coli

Negative/g

 

Salmonella

Negative/25g

 

Staphylococcus Aureus

Negative/25g

Conclusion:

Conform with enterprise specification .

 

 

What are the pharmacological effects of Vitamin K1?

Vitamin K1 is a yellow, clear, viscous oily liquid. Vitamin K1 is a fat soluble vitamin. Vitamin K is an essential substance for the liver to synthesize prothrombin, and its function is to promote the conversion of prothrombin precursor into prothrombin. Lack of prothrombin can cause hypophrombinemia and coagulation disorders. When vitamin K is dissolved in the lipids of mitochondrial membrane, it can play an electron transfer role. Vitamin K can also increase intestinal peristalsis and secretion function. When lacking vitamin K, smooth muscle tension and contraction are weakened, and it can also affect the metabolism of some hormones. Such as delaying the breakdown of glucocorticoids in the liver and having a similar effect to hydrocortisone, long-term use of vitamin K can increase thyroid endocrine activity, etc. We can summarize the functions of this product as follows:Vitamin K1 is often added to toothpaste to alleviate gum bleeding.
1. As an auxiliary factor, it participates in the synthesis of coagulation factors II, VII, XII, and X in the liver, preventing and treating bleeding caused by vitamin K1 powder deficiency.
2. Promote the conversion of fibrinogen into fibrin and improve the elasticity of plasma fibrin clots.
3. It is necessary to participate in the oxidation process to ensure the normal metabolism of phosphate transfer and high-energy phosphate compounds in the body.
4. Increase intestinal peristalsis and secretion function, and enhance the tension of the common bile duct sphincter.

 

Why does a lack of vitamin K cause blood flow to persist?

Phytomenadione is a naphthoquinone compound, which comes from many plants. Food and green vegetables are rich in vitamin K1, which is mainly absorbed in the ileum, and its absorption depends on the normal absorption of bile salts and body fat. However, the storage of vitamin K1 powder in the body is very small, and it can be completely consumed in the body in 3 ~ 4 weeks, so it needs to be obtained from gastrointestinal food frequently, and vitamin K is necessary for the liver to synthesize four coagulation factors (active coagulation factor II (prothrombin), coagulation factor VII, coagulation factor VIII and coagulation factor VIII). If there is an obstacle in the absorption process, the four coagulation factors synthesized by the liver are abnormal protein molecules, and their ability to catalyze coagulation is greatly reduced. According to the research of modern medicine, vitamin K is a cofactor of γ carboxylation of glutamic acid. Without vitamin K, the γ-carboxylation of the above coagulation factors can not be carried out, which leads to the decrease of these coagulation factors in blood, which leads to coagulation disorder or slow coagulation, and even causes more serious bleeding symptoms, mainly manifested as skin mucosal bleeding, visceral bleeding, post-traumatic surgery bleeding, neonatal bleeding and other deep tissue bleeding.

 

What are the uses of Vitamin K1?

Vitamin K1, as a pharmaceutical preparation, is clinically applied to the prevention and treatment of thrombocytopenia, vitamin K1 deficiency, neonatal spontaneous hemorrhage, bleeding caused by obstructive jaundice, biliary fistula and chronic diarrhea, and hypoproteinemia caused by coumarins and sodium salicylate. Vitamins also have the function of relieving pain and bronchospasm, and have obvious effects on colic caused by visceral smooth muscle colic, bile duct spasm and intestinal spasm. Vitamin K1 powder can also be used as an additive for multi-dimensional food and livestock feed.

 

A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide vitamin K1 powder etcat a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

 

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