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Salcaprozate Sodium CAS 203787-91-1

Salcaprozate Sodium CAS 203787-91-1

Product Name:Salcaprozate Sodium
Synonym:E414;Salcaprozate sodium;SNAC
CAS NO.:203787-91-1
EINECS NO.:231-019-4
Molecular Formula:C15H22NNaO4
Purity & Grade: 99%; Medicine grade
Character:White Powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
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Description
 
 

Product description

Salcaprozate Sodium

Salcaprozate Sodium, abbreviated as SNAC, is a dicarbon phosphate compound absorption enhancer used for the treatment of gastrointestinal diseases, especially suitable for gastrointestinal diseases caused by poor absorption of dicarbon phosphate compounds. Salcaprozate Sodium is a synthetic N-acetylated amino acid derivative of salicylic acid. It was discovered during the screening of carrier-based osmotic promoters, which can "accompany" poorly permeable payloads through the intestine. This article will introduce its mechanism of promoting the absorption of semaglutide.

Salcaprozate Sodium (SNAC) is an absorption enhancer and has the potential to be used as a delivery agent for heparin and insulin in its application form. Salcaprozate sodium can increase lipophilicity caused by the complexation of non-covalent macromolecules, thereby increasing passive transcellular permeation of small intestinal epithelial cells.

Salcaprozate Sodium HTML

 

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COA

 

Items Standard Results
Character Appearence White,yellowish or slightly pinkish,crystalline
powder		 Off-white crystalline
powder
Identification HPLC The retention time of the main peak of the
Sample solution corresponds to that of the
Standard solution.		 Conforms
Inspect Relevant substance Impurity A≤0.15% Not detected
Impurity E≤0.15% Not detected
Impurity G≤0.5% Not detected
The maximum unknow single impurity≤0.1% Not detected
Total impurities≤1.0% Not detected
Water ≤3.0% 0.5%
Residual solvent Methyl alcohol≤0.5% Not detected
sopropyl alcohol≤0.5% 0.1%
DMF≤0.088% Not detected
Ethyl alcohol≤0.5% Not detected
Benzene≤0.0002% Not detected
Assay Calculated as anhydrous:98.0%～102.0% 100.1%
Conclusion Conform with enterprise specification

 

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Salcaprozate Sodium MF

Boiling point: 521.7 ° C at 760 mmHg
Molecular formula: C15H20NNaO4
Molecular weight: 301.313
Flash point: 269.3 ° C
Precise mass: 301.128998
PSA 89.46000
LogP 1.60340

 

What is salcaprozate sodium used for?

Salcaprozate Sodium is supplied by Actylis in the form of a white to off-white solid that is hygroscopic in nature. Salcaprozate Sodium is used as an excipient in the formulation of pharmaceutical products.

 

What is salcaprozate sodium drugbank?

Salcaprozate sodium (SNAC) is an intestinal permeation enhancer that is used in drug formulations particularly for macromolecules and poorly permeable compounds.

 

Is salcaprozate sodium safe?

The intestinal permeation enhancer (PE) salcaprozate sodium (SNAC) has Generally Regarded As Safe (GRAS) status and is a component of an approved peptide formulation.

 

Semaglutide absorbent aid

 

Novo Nordisk has proposed a new mechanism of action for its GLP-1 analogue semaglutide tablets, taking advantage of the effect of Salcaprozate Sodium in the stomach. The theoretical basis is that SNAC forms a complex with semaglutide, causing a temporary increase in the local pH value around. This effect protects semaglutide from the influence of pepsin and increases its performance in terms of solubility, thereby increasing the concentration-dependent flux of semaglutide through the gastric mucosa. This mechanism has a high specificity for semaglutide because similar studies have not led to an increase in the flux of in vitro gastric epithelial models compared with the SNAC and liraglutide mixture.

 

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Shipping Methods

 

Transportation Time

Shipping method

Cargo weight requirements

 Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
 
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
 
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

 

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