What is N-Acetyl-L-glutamic acid ?
N-Acetyl-L-glutamic acid is a white crystalline powder with sour taste and no optical rotation ,The melting point is about 280℃, and it is stable under acidic and alkaline conditions. Solubility: easily soluble in water,N-Acetyl-L-glutamic acid is a non-essential amino acid, which can be synthesized by the human body. Excessive intake may cause a burden on the liver.
| Product name | N-Acetyl-L-glutamic acid |
| CAS | 1188-37-0 |
| Molecular formula | C7H11NO5 |
| Molecular weight | 189.17 |
| EINECS Number | 214-708-4 |
| melting point | 194-196 °C(lit.) |
| boiling point | 324.41°C (rough estimate) |
| density | 1.4119 (rough estimate) |
| specific rotation | -16 º (c=1, water) |
| Storage condition | Room temperature preservation |
What are the main uses of N-Acetyl-L-glutamic acid?
N-Acetyl-L-glutamic acid is widely used in medicine, food, cosmetics and other fields. Medically, it can be used as a medicine for improving brain function, and can be used for treating diseases such as hepatic coma, brain trauma, brain tumor, paralysis, mental retardation, and memory disorder.
1. Medicine and clinic
N-Acetyl-L-glutamic acid is used for nutritional supplement for patients with liver disease and heart disease.
As an amino acid infusion component, it can be used for adjuvant treatment of metabolic diseases.
It Used in drug synthesis, such as precursors of antibiotics and sedatives.
It has the functions of improving nerve cell metabolism, maintaining nerve stress ability and reducing blood ammonia, and can penetrate the blood-brain barrier, and can be used for the treatment of symptoms such as brain injury, coma, coma, hemiplegia, paraplegia, sequelae of brain injury, mental retardation and nervous headache, N-Acetyl-L-glutamic acid mainly by decomposing into glutamic acid and γ -aminobutyric acid through the blood-brain barrier. Glutamate can participate in the information transmission of the central nervous system, and γ -aminobutyric acid can also participate in the metabolism of substances in the brain to improve nerves.
2. Industrial application
Biomedical intermediates, N-Acetyl-L-glutamic acid used in the research and development of antibiotics and antiviral drugs.
Composition of microbial culture medium, promoting cell growth.
Metal complexing agent is used for the detection and separation of heavy metal ions.
3. Cosmetics and food
It can also enhance the flavor of food and serve as a natural preservative. -Cosmetics are used for skin repair and nutritional supplement.
Where does N-Acetyl-L-glutamic acid come from?
Natural existence and artificial production
1. Natural existence
It exists naturally in human body, and participates in physiological processes such as neurotransmitter synthesis in brain, gastrointestinal function regulation, nitrogen metabolism and acid-base balance maintenance.
2. Manual production
It can also be produced by chemical synthesis or biological fermentation. Chemical synthesis method realizes large-scale production through the above-mentioned reaction formula, while biological fermentation law uses microorganisms (such as Corynebacterium glutamicum) to efficiently convert glutamic acid into N-Acetyl-L-glutamic acid.
Product Specification
| Item | Specifications | Result |
|
Appearance |
White crystalline powder | Complies |
| Assay (HPLC basis on drying) |
89.1%~110.1% | 99.70% |
| Heavy Metal | ||
| Lead (Pb) | ≤2.0ppm | Complies |
| (As) | ≤1.0ppm | Complies |
| (Cd) | ≤1.0ppm | Complies |
| (Hg) | ≤0.1ppm | Complies |
| Microorganism | ||
| Total Plate Count | ≤1000cfu/g | Complies |
| Yeasts and Molds | ≤100cfu/g | Complies |
| Saimonella | Negative/25g | Complies |
| E.coli | Negative | Complies |
| Conclusion: The test results are conformed to the in-house specification | ||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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