What is Cobamamide ?
Cobamamide is one of the series products of vitamin B12, and its chemical name is: 5,6-dimethylbenzimidazole -5'- deoxyadenine nucleoside cobalamin, which is an octahedral cobalamin complex. Glandular glycoside cobalamin is dark red crystalline and amorphous powder, which has strong hygroscopicity and is easy to decompose when exposed to light.Cobamamide is an important variety of vitamin B12 series products, which belongs to raw materials and has important medical value. Red needle crystal or crystalline powder, odorless, tasteless and hygroscopic.
| Product name | Cobamamide |
| CAS | 13870-90-1 |
| Molecular formula | C72H99CoN18O17P |
| Molecular weight | 1578.6 |
| EINECS | 237-627-6 |
| solubility | Soluble in water (slight, ultrasonic treatment) |
| Acidity coefficient (pKa) | 3.5(at 25℃) |
| stability | hygroscopicity |
| Storage condition | -20°C |
What is the physiological function of Cobamamide ?
It is the same kind of cyanocobaltous vitamin B12, which is an important coenzyme for cell synthesis of nucleotides, participates in methyl conversion and folic acid metabolism in vivo, and promotes the reduction of methyl folic acid into tetrahydrofolic acid. It is also involved in the tricarboxylic acid cycle, which is very important for the formation of lipoproteins in the myelin sheath. It can make thiolase in a working state, thus participating in a wide range of protein and fat metabolism. Cobamamide can promote the development and maturation of red blood cells, which is an essential factor for the complete formation of nerve sheath spinal cord fibers and maintaining the function of epithelial cells in digestive system.
Cobamamide is usually a commonly used vitamin medicine in clinic. If patients suffer from malnutrition anemia, pregnancy anemia, megaloblastic anemia and so on due to vitamin B12 deficiency, cobalamin adenosine can usually supplement the needed vitamins for the human body, which can alleviate the discomfort symptoms to some extent.
This product is usually a necessary substance for cell growth and proliferation and maintaining the integrity of nerve myelin sheath. It can also play a role in nourishing nerves. It can usually have a good therapeutic effect on diseases such as polyneuritis and radiculitis, and can also assist in the treatment of leukopenia caused by radiation and drugs.
What drug does Cobamamide interact with?
Cobamamide is a vitamin medicine, which is made from the fermentation broth for producing chlortetracycline or streptomycin through hydrolysis, sodium cyanide cyanidation, acidification and refining.
1. It should not be mixed with chlorpromazine, vitamin C and vitamin K in the same container.
2. Chloramphenicol reduces its absorption.
3. This product can be combined with vitamin B12 to reduce its absorption.
4. This product is incompatible with glucose solution.
5. Cobamamide cannot be used with sodium p-aminosalicylate.
Product Specification
| Item | Specifications | Result |
| Appearance | Red needle crystal or crystalline powder | Organoleptic |
| Loss on drying | ≤10.0% | 6.0% |
| Assay | 98.5~102.0% | 99.75% |
| Identification C |
HPLC: The retention time of the major peak of the sample solution corresponds to that of the standard solution. |
conforms |
| Heavy metals | ≤10ppm | 5ppm |
| 7β, 8β-Lactocyanocobalamin | ≤1.0% | conforms |
| 34-Methylcyanocobalamin | ≤2.0% | conforms |
| 8-Epi-cyanocobalamin | ≤1.0% | conforms |
| Microbial limit | Total Aerobic Microbial Count: NMT 100 CFU/g | <100 CFU/g |
| Total Yeasts and Moulds Count: NMT 10 CFU/g | <10 CFU/g | |
| E.Coli: Negative | Negative | |
| Salmonella: Negative | Negative | |
|
S.Aureus: Negative |
Negative | |
| Conclusion: The test results are conformed to the in-house specification | ||
How and where to buy Cobamamide wholesale?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details, Click email：sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales7@faithfulbio.com Now.
Disclaimer: The articles published on this website are mainly used for academic research and technical discussions, which is dialectical and does not mean that this website agrees with all of its views. Please carefully screen. If there is any infringement or other dispute, please contact the administrator. We are not responsible for the consequences of using the information and services on this website.
Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
Hot Tags: cobamamide cas 13870-90-1, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China