Terbinafine Powder CAS 91161-71-6

Terbinafine Powder CAS 91161-71-6

Product Name:Terbinafine
CAS NO.:91161-71-6
Molecular Formula: C21H25N
Synonym:Terbinafine;LAMISIL;TERBINAFINE;sf-86-327;Terbinafine hydrochloride;rerbinafine;(E)-Terbinafine;
Purity: Medicine grade 99%;Customizable
Test Method:HPLC/UV
MOQ & Package: 10g,100g,1kg etc Sub-package
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
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Description

Terbinafine Powder can treat infections of the skin, hair, and nails caused by Trichophyton, Microsporidia canis, and Trichophyton flocs. It can also treat various ringworm diseases, as well as skin yeast infections caused by Candida, and onychomycosis caused by Aspergillus. Terbinafine hydrochloride is an allylamine antifungal drug that inhibits the synthesis of ergosterol in fungal cells by inhibiting squalene cyclooxygenase and causing squalene to accumulate in cells, thus exerting bactericidal effects.

Items

Standard

Result

Appearance

White oralmost white powder

Complies

Solubility

Freely soluble in anhydrous ethanol and
in methanol ,slightly soluble in acetone,
very slightly or slightly soluble in water

Complies

Identification

IR absorption spectrum of sample should be
consistent with spectrum of standard It gives
reaction (a)of chlorides using anhydrous
ethanol as solvent

Complies

Related
Substances

Impurity B≤0.15%
Impurity E≤0.05%
Unspecified impurity ≤0.10%
Total impurities≤0.30%

N.D
N.D
0.05%
0.14%

Loss on drying

<5ppm

0.06%

Sulfated ash

<10ppm

0.06%

Residual solvents

Isopropyl alcohol≤5000ppm
Ethyl acetate≤5000ppm
Trichloromethane≤60ppm

198ppm
321ppm
43ppm

Assay

99.0~101.0

99.5%

Amphetamine type antifungal drugs have a wider antibacterial spectrum and higher antifungal activity than naltifen. It can selectively inhibit the fungal squalene cyclooxygenase, blocking the squalene epoxidation reaction during fungal cell membrane formation and disrupting the formation of fungal cell membranes, achieving the effect of killing or inhibiting fungi. Safe, low toxicity, minimal side effects, good oral and topical tolerance, no teratogenicity or embryotoxicity. Clinically used for various skin fungal infections (tinea pedis, tinea pedis, and tinea corporis) and nail fungal infections.

 

Which is better, terbinafine or benzimidazole?

In clinical practice, terbinafine and benzimidazole refer to terbinafine preparations and benzimidazole preparations, and neither is better. Both terbinafine preparations and benzimidazole preparations belong to antifungal drugs, which can exert antifungal effects by inhibiting the synthesis of fungal cell membranes. It is recommended to choose the appropriate drug treatment under the guidance of a doctor.
1. Terbinafine preparation: the commonly used clinical dosage forms are terbinafine hydrochloride tablet, terbinafine hydrochloride cream, terbinafine hydrochloride spray, etc. Terbinafine hydrochloride cream and terbinafine hydrochloride spray are mainly applicable to the treatment of tinea manus, tinea pedis, tinea corporis, tinea cruris and tinea versicolor caused by sensitive fungi, while terbinafine hydrochloride tablet is mainly used in clinical treatment of fungal infections of skin and hair caused by dermatophytes such as tinea, microsporus canis and dermatophyte floccosus.
2. Benzonazole preparations: Benzonazole belongs to a type of active pharmaceutical ingredient, commonly used in clinical settings as Benzonazole cream, Benzonazole vaginal tablets, etc. Among them, Benzonazole cream is used in clinical practice to treat various skin fungal diseases, such as tinea manus, tinea pedis, tinea corporis, tinea pedis, and tinea versicolor. Benzonazole vaginal tablets are mainly used to treat candidal vulvovaginitis.
If there are symptoms of fungal infection on the skin, such as skin erythema, papules, blisters, and flaking, it is recommended to seek medical attention at a dermatologist in a hospital to complete fungal microscopy examination, fungal culture, etc. The doctor may guide the use of terbinafine preparations or benzimidazole preparations, both of which are commonly used antifungal drugs and there is no better option.

91161-71-6 Terbinafine

51-17-2 Benzimidazole

84625-61-6 Itraconazole

91161-71-6 Terbinafine 51-17-2 Benzimidazole 84625-61-6 Itraconazole

Our company can provide various Benzimidazole,Terbinafine,Itraconazole etc. If you are interested, please contact us via email:sales6@faithfulbio.com

 

Which is more effective, terbinafine hydrochloride or itraconazole?

Terbinafine hydrochloride and itraconazole are two commonly used antifungal drugs, both of which have certain effects, but their specific curative effects and indications are different.

Terbinafine hydrochloride is a broad-spectrum antifungal drug, and its mechanism of action is to inhibit the synthesis of fungal cell membrane, thus achieving bactericidal effect. Terbinafine hydrochloride has a good effect in treating superficial fungal infections such as tinea manuum, tinea pedis and tinea corporis, and can effectively relieve symptoms. However, terbinafine hydrochloride also has some side effects, such as hepatotoxicity, nephrotoxicity, nervous system side effects, etc. Therefore, it is necessary to pay attention to the dosage and administration time in order to avoid adverse reactions.

Itraconazole is an antifungal drug, and its mechanism of action is to inhibit the synthesis of fungal cells, thus achieving bactericidal effect. Itraconazole also has a good effect in the treatment of fungal infection, which can relieve symptoms, but it also has great side effects, such as hepatotoxicity and nervous system side effects. Therefore, when using itraconazole, it is necessary to pay attention to the dosage and administration time to avoid adverse reactions.

In a word, terbinafine hydrochloride and itraconazole are commonly used antifungal drugs, and their curative effects and indications are different, so they need to be selected according to specific conditions to achieve the best therapeutic effect.

 

Is Terbinafine spray Useful for Malassezia Folliculitis?

Terbinafine powder can be made into terbinafine hydrochloride spray. Terbinafine hydrochloride spray is useful for Malassezia folliculitis. It is recommended to go to the hospital dermatology department in time and use it under the guidance of a doctor.

Malassezia folliculitis is a common skin disease, which is caused by malassezia infecting hair follicles. This fungus usually grows on human skin, but when skin oil secretion is excessive or the immune system is weakened, Malassezia will over-multiply, resulting in inflammation of hair follicles, redness, itching and other symptoms.

Terbinafine hydrochloride spray is an antifungal drug, which inhibits and kills fungi by blocking the key steps in the formation of fungal cell membrane and interfering with sterol synthesis of fungi. This drug has broad-spectrum antibacterial activity and is effective against many fungi.

For patients with malassezia folliculitis, terbinafine hydrochloride spray can directly act on malassezia to inhibit its growth and reproduction, thus alleviating the symptoms of folliculitis. In addition, it can also reduce skin inflammation and relieve discomfort such as redness and itching.

Although terbinafine hydrochloride spray is effective in treating Malassezia folliculitis, attention should still be paid to its use. It should be used according to the course of treatment according to the doctor's advice, and it is not allowed to stop the drug or change the dose at will. Pay attention to the side effects and precautions of drugs, such as allergic reactions.

For the treatment of malassezia folliculitis, in addition to terbinafine hydrochloride spray, drugs such as itraconazole capsules and fluconazole capsules can be taken orally according to the doctor's advice, but attention should be paid to liver and kidney functions to avoid excessive use.

 

A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Can provide you with a good price.Our company can provide various Benzimidazole,Terbinafine,Itraconazole etc. If you are interested, please contact us


We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

 

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email :sales6@faithfulbio.com   . Our team is committed to ensuring the complete satisfaction of customers.

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