Product description

Resmetirom API Powder stands as a cutting-edge active compound featuring outstanding target selectivity, and it marks a major advancement in managing adult non-alcoholic steatohepatitis. This compound acts on particular receptors within the liver, boasting remarkable tissue specificity. It works accurately on liver targets while barely interfering with receptors located in the heart, bones and other body parts, which greatly lowers the risks brought by non-specific effects across the body.
In terms of physiological regulation, it can efficiently modulate lipid metabolism inside the liver. It curbs the build-up and generation of redundant fats, speeds up the decomposition and turnover of fatty acids, and thereby cuts down fat deposits in the liver step by step. Additionally, it eases inflammatory reactions in the liver and holds back the development of pathological fibrosis. It also helps improve blood lipid profiles and creates a healthier state for the body's overall lipid metabolism.
In its physical form, Resmetirom API Powder is a white to off-white crystalline powder, with some formulations exhibiting a light yellow texture; its overall properties are stable. Resmetirom is primarily aimed at individuals with non-alcoholic steatohepatitis accompanied by mild to moderate liver fibrosis. It is designed to be used in conjunction with a healthy diet and a regular lifestyle of rest and exercise. It is also suitable for individuals with related conditions such as obesity, metabolic abnormalities, and blood sugar fluctuations.

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COA
| Test Item | Specification | Result |
| Appearance | White or off-white powder | Off-white powder |
| Identification | By HPLC | Complies |
| Melting Point | 120ºC~130ºC | 126ºC |
| Loss on Drying | ≤1.00% | 0.21% |
| Heavy Metals | ≤ 10ppm | Complies |
| Sulfated Ash | ≤ 0.10% | 0.03% |
| Microbiological Test | Coliforms:Negative | Negative |
| Salmonella: Negative | Complies | |
| Total plate count: ≤1000 CFU/g | Pass | |
| Yeast&Mold: ≤50 CFU/g | Pass | |
| Related Substances | Impurity A: ≤0.30% | 0.18% |
| Other unknown impurity: ≤0.10% | 0.07% | |
| Total Impurities: ≤0.50% | 0.42% | |
| Assay | ≥ 98.0% | 99.50% |
| Conclusion | Conform with enterprise specification | |
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Density 1.65±0.1 g/cm3 (20 °C, 760 mmHg)
Molecular Formula C17H12Cl2N6O4
Molecular Weight 435.22100
Exact Mass 434.03000
PSA 146.52000
LogP 2.09828
InChIKey FDBYIYFVSAHJLY-UHFFFAOYSA-N
Mechanism of action of Resmetirom
Precise targeting: Selectively acts on the beta receptors of thyroid hormones in the liver, with almost no impact on homologous receptors in the heart, bones, and other parts of the body, resulting in higher safety.
Reduces liver fat accumulation: Inhibits liver lipid synthesis, accelerates fatty acid catabolism, and gradually reduces intrahepatic fat content.
Anti-inflammatory and liver-protective: Reduces local liver inflammation and improves the state of inflammatory liver damage.
Delays liver fibrosis: Inhibits abnormal proliferation of fibrous tissue and slows the progression of liver fibrosis.
Regulates systemic blood lipids: Optimizes lipid metabolism and improves overall blood lipid levels.
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why choose us
Our Factory


Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales4@faithfulbio.com
FAQ
01. What are the effects of Resmetirom on liver inflammation and fibrosis?
Resmetirom API Powder can soothe abnormal liver inflammation and inhibit abnormal proliferation of fibrous tissue, thus slowing the progression of fibrosis.
02. Can Resmetirom regulate blood lipid levels?
Yes, it can effectively regulate blood lipid levels and optimize the overall lipid metabolism environment.
03. Where can I buy Resmetirom API Powder?
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