Olivetolic Acid CAS 491-72-5

What is Olivetolcarboxylic acid?

Olivetolcarboxylic acid is a polyketide compound derived from a tetraketide precursor and is a key intermediate in the biosynthesis of various secondary metabolites in plants. The structure of Olivetolic acid is similar to other polyketides, such as the well-known polyketide synthase product lovastatin, which is a cholesterol derivative. In recent years, Olivetolcarboxylic acid has attracted increasing attention due to its diverse biological activities and potential applications.

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What are the uses of Olivetolcarboxylic acid?

The primary use of olivetolic carboxylic acid is as a key precursor in the biosynthesis of cannabinoids. In the Cannabis sativa plant, it is a universal precursor for the synthesis of all natural cannabinoids, producing cannabis (Cannabigerovarol) via enzymatic reactions, and further converting into the two well-known products. Therefore, this compound is widely used as an analytical reference standard in cannabinoid research and forensic identification to aid in the study and detection of the metabolic pathways and components of related substances.

Furthermore, research has revealed potential applications of Olivetolic acid in other fields. For example, animal experiments have shown that olivetolic carboxylic acid possesses anticonvulsant activity, raising the seizure threshold. In cell experiments, it has also been observed to inhibit protein kinase activity and induce apoptosis in specific cancer cells. As an organic chemical raw material, it is also used in the preparation of pharmaceutical intermediates and in studies of the antibacterial activity of some agrochemicals. Currently, all these applications are strictly limited to research and laboratory settings and are not suitable for human or veterinary use.

Who cannot use Olivetolcarboxylic acid?

According to current scientific research, there is no clearly defined group of people who should not use Olivetolcarboxylic acid. This is mainly because it is currently limited to rigorous research and laboratory use and has not yet been approved as a supplement or consumer product in any form.

However, based on the commonalities of its parent structure and the principle of caution in scientific research, the following groups generally need to exercise special caution and should not attempt to use it in non-professional settings:
Pregnant and breastfeeding women: Due to the lack of relevant safety data, and the fact that any biologically active precursor may have unknown effects on the fetus or infant.

Persons with impaired liver or kidney function: The metabolic and excretion pathways of Olivetolic acid in the body are not yet cleared. Individuals with impaired liver or kidney function may not be able to effectively eliminate the substance, increasing the risk of cumulative toxicity.

Persons allergic to compounds with similar structures: Although direct allergy data for Olivetolcarboxylic acid is lacking, individuals with a history of allergies to similar compounds theoretically face the risk of cross-reactions.

MF of Olivetolcarboxylic acid

Molecular formula	C12H16O4
Molecular weight	224.25
Melting point	143 °C
Acidity coefficient	3.41±0.34
Density	1.237±0.06 g/cm3
boiling point	403.9±25.0 °C

Specification

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Q1: What are our markets?
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