Product Introduction
Protocatechualdehyde is a light yellow crystal. The melting point is 153-154℃. It is soluble in hot water and easily soluble in ethanol and ether. It contains two phenolic hydroxyl groups in its structure and has a certain acidity. It can react with alkaline substances to produce corresponding salts. Since it contains two phenolic hydroxyl groups, it can participate in nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons to produce esters, ethers and other compounds. In addition, the aldehyde group is a highly active functional group that can be easily converted into carboxyl groups, ester groups, unsaturated double bonds, etc.
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| Protocatechualdehyde Picture | Protocatechualdehyde MF |
Product Application
Protocatechualdehyde is easily soluble in ether. At 78℃, 79g can be dissolved in 100ml ethanol. At 20℃, 5g can be dissolved in 100ml water. At 99℃, 33g can be dissolved in 100ml water. It is slightly soluble in benzene and petroleum ether. Melting point 153～154℃ (decomposition). Median lethal dose (mouse, intravenous) 56mg/kg. Irritating. Uses: biochemical research. Organic synthesis, an important pharmaceutical intermediate, can be used to synthesize a variety of antibiotics and anti-inflammatory drugs.
The content of protocatechuic aldehyde in Baike ointment was determined by HPLC. Methods: Diamonsil C_(18) column (250mm×4.6mm, 5μm) was used, and the mobile phase was methanol-water solution containing 0.5% acetic acid (21:79). The flow rate was 1.5mL·min~(-1), and the detection wavelength was 281nm. Results: Protocatechuic aldehyde had a good linear relationship in the range of 5.82～58.20μg·mL~(-1), r=0.9999, the average recovery rate was 99.64%, and RSD=1.75%. Conclusion: This method can be used as a method to control the quality of Baike ointment.
Protocatechualdehyde (50, 100 μM, 24 hours) treated MCF-7 cells increased 1.9-fold and 2.6-fold at 50 μM and 100 μM concentrations, respectively. PCA inhibited the proliferation of estrogen receptor (ER) positive (MCF-7) breast cancer cells, but not ER negative (MDA-MB-231) breast cancer cells. Protocatechualdehyde (0, 100, 200 μM, 48 hours in HCT116 and SW480 cells) affected the enzymatic activity of HDAC, and PCA treatment was observed to inhibit HDAC activity in a dose-dependent manner.
Product Specification
| Item | Specifications | Results |
| Appearance | Slightly Brown Powder | Conforms |
| Loss on Drying | ≤1.0% | 0.50% |
| Melting Point | 153.0-155.0°C | 153.6-154.5°C |
| Assay | ≥99.0% (by HPLC) | 99.70% |
| Conclusion | The results conforms with enterprise standards |
How To Obtain SamplesProtocatechualdehyde?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Protocatechualdehyde.
The Best Protocatechualdehyde Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Protocatechualdehyde?
Faithfulbio specialize in Protocatechualdehyde for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Protocatechualdehyde for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Protocatechualdehyde?
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