Ambrisentan Powder CAS 177036-94-1
Product Name:Ambrisentan
Synonym:Letairis;ambrisentan
CAS NO.:177036-94-1
EINECS NO.:658-059-9
Molecular Formula:C22H22N2O4
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Like all endothelin receptor antagonists, Ambrisentan is contraindicated in pregnant women as well as those who are trying to become pregnant, due to the potential for teratogenic effects on the fetus.
Ambrisentan Powder, is a drug used for the treatment of pulmonary hypertension. It is an endothelin receptor antagonist.

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COA
| Item | Standard | Test Results |
| Appearance | White to off-white powder | Conforms |
| Identification | IR | Conforms |
| Loss on drying | ≤5.0% | 0.11% |
| Related Substance | Single impurity: ≤0.3% | 0.14% |
| Total impurities:≤1.0% | 0.30% | |
| R-Isomer | ≤ 0.5% | 0.13% |
| S-2-Hydroxy-3- Methoxy-3,3-Diphenyl Propionic Acid | ≤ 0.2% | 0.12% |
| Residual solvents | Meet the requirement | Conforms |
| Assay | 98.5~101% | 99.80% |
| Conclusion | Conform with enterprise specification | |
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What type of drug is ambrisentan?
Ambrisentan Powder is in a class of medications called endothelin receptor antagonists.
What is Bosentan and ambrisentan?
Bosentan, ambrisentan, and macitentan are endothelin receptor antagonists (ERAs), currently available in Australia for treatment of pulmonary arterial hypertension (PAH).
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Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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